Clinical Trials in Austin

Showing 5921-5940 of 15,205 trials

Multifactorial Risk Assessment for Breast & Ovarian Cancer Risk Detection

NCT04668521

The objective of this project is to validate a next-generation assay that utilizes both the protein biomarkers of our already established ovarian cancer risk assessment combined with a molecular profile in both germline and early somatic detection.

Adnexal MassGermline BRCA1 Gene MutationGermline BRCA2 Gene Mutation+1 more

Aspira Women's Health215 participantsStarted May 2020

Austin, Texas, United States

COMPLETEDPhase 274 miles

A Study to Evaluate Patient Preference and Satisfaction of Subcutaneous Administration of the Fixed-Dose Combination of Pertuzumab and Trastuzumab in Participants With HER2-Positive Early Breast Cancer

NCT03674112

This is a Phase II, randomized, multicentre, multinational, open-label, cross-over study in adult patients who have completed neoadjuvant chemotherapy with neoadjuvant pertuzumab and trastuzumab and have undergone surgical treatment of human epidermal growth factor receptor 2 (HER2)-positive early breast cancer. The study will consist of two adjuvant treatment periods: a treatment cross-over period and a treatment continuation period. It will evaluate participant-reported preference for a subcutaneously administered fixed-dose combination formulation (FDC SC) of pertuzumab and trastuzumab compared with intravenously (IV) administered pertuzumab and trastuzumab formulations. The study will also evaluate participant-reported satisfaction with pertuzumab and trastuzumab FDC SC and health-related quality of life outcomes; healthcare professionals' perceptions of time/resource use and convenience of pertuzumab and trastuzumab FDC SC compared with pertuzumab and trastuzumab IV formulations; as well as the safety and efficacy of each study regimen.

HER2-Positive Early Breast Cancer

Hoffmann-La Roche160 participantsStarted Dec 2018

Lakewood, Colorado, United States • Peoria, Illinois, United States • Wichita, Kansas, United States +37 more locations

Multifactorial Risk Assessment for Breast & Ovarian Cancer Risk Detection

A Study to Evaluate Patient Preference and Satisfaction of Subcutaneous Administration of the Fixed-Dose Combination of Pertuzumab and Trastuzumab in Participants With HER2-Positive Early Breast Cancer

Find Trials by Condition in Austin

MSB11022 in Moderate to Severe Chronic Plaque Psoriasis

Pediatric Study to Evaluate Risk of Developing Essential Fatty Acid Deficiency When Receiving Clinolipid or Standard-of-Care Lipid Emulsion (Part A)

A Study of TAK-994 in Adults With Narcolepsy

A Phase I Pharmacokinetic Study of TVB-2640 (Denifanstat) in Subjects With Mild, Moderate, or Severe Hepatic Impairment Compared to Subjects With Normal Hepatic Function

A Phase 1b Trial of ATRC-101 in Adults With Advanced Solid Malignancies

Safety and Efficacy of Activated Recombinant Human Factor VII in Haemophilia Patients With Inhibitors During and After Major Surgery

Clinical Trial of Solanezumab for Older Individuals Who May be at Risk for Memory Loss

Study Investigating NTLA-5001 in Subjects With Acute Myeloid Leukemia

Digital Ischemic Lesions in Scleroderma Treated With Oral Treprostinil Diethanolamine

VIR-7831 for Inpatients With COVID-19 (An ACTIV-3/TICO Treatment Trial)

The Efficacy and Safety of Cobitolimod in Participants With Moderate to Severe Active Left-Sided Ulcerative Colitis

Study to Evaluate the Safety and Efficacy of KITE-439 in HLA-A*02:01+ Adults With Relapsed/Refractory HPV16+ Cancers

Trial in Non-cystic Fibrosis Bronchiectasis Patients With Chronic Lung Infections Treated With Colistimethate Sodium.

A Study of the Effectiveness And Safety Of Lidoderm® As Add-On Treatment in Patients With Postherpetic Neuralgia, Diabetic Neuropathy, or Low Back Pain

A Study of Lanadelumab in Teenagers and Adults to Prevent Acute Attacks of Non-histaminergic Angioedema With Normal C1-Inhibitor (C1-INH)

A Study Of Lidocaine Patch 5% Alone, Gabapentin Alone, And Lidocaine Patch 5% And Gabapentin In Combination For The Relief Of Pain In Patients With Diverse Peripheral Neuropathic Pain Conditions

CD40 Agonistic Antibody APX005M (Sotigalimab) in Combination With Nivolumab

Evaluation of Safety and Tolerability of ENT-01 for the Treatment of Parkinson's Disease Related Constipation