Clinical Trials in Austin

Showing 2661-2680 of 13,060 trials

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Lacosamide in Neonates With Repeated Electroencephalographic Neonatal Seizures

NCT04519645

The purpose of the study is to evaluate the efficacy of lacosamide (LCM) versus an Active Comparator chosen based on standard of care (StOC) in severe and nonsevere seizure burden (defined as total minutes of electroencephalographic neonatal seizures (ENS) per hour) in neonates with seizures that are not adequately controlled with previous anti-epileptic drug (AED) treatment.

Electroencephalographic Neonatal SeizuresEpilepsy

UCB Biopharma SRL29 participantsStarted Mar 2021

La Jolla, California, United States • Long Beach, California, United States • Los Angeles, California, United States +15 more locations

WITHDRAWNPhase 1/2< 1 mile

Study of Selinexor in Combination With Backbone Treatments or Novel Therapies In Participants With Relapsed or Refractory (RR) Diffuse Large B-Cell Lymphoma (DLBCL)

NCT04607772

This is a Phase 1/2, multicenter, open-label study to evaluate the efficacy, and safety of various combinations with selinexor in participants with RR DLBCL. The study will be conducted in two phases: Phase 1 and 2. The Phase 1 of the study will be a standard 3 + 3 dose escalation to determine the maximal tolerated dose (MTD), recommended Phase 2 dose (RP2D) for each treatment arm, and assess the dose limiting toxicities (DLTs). The Phase 2 of the study will be a dose expansion study to assess the efficacy and safety of for RP2D selected at the end of Phase 1 of the study for each treatment arm.

Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Karyopharm Therapeutics IncStarted Nov 2020

Tucson, Arizona, United States • Encinitas, California, United States • La Jolla, California, United States +15 more locations

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Lacosamide in Neonates With Repeated Electroencephalographic Neonatal Seizures

Study of Selinexor in Combination With Backbone Treatments or Novel Therapies In Participants With Relapsed or Refractory (RR) Diffuse Large B-Cell Lymphoma (DLBCL)

Find Trials by Condition in Austin

Central Vein Sign: a Diagnostic Biomarker in Multiple Sclerosis

Efficacy and Safety of Four Doses of Cenerimod Compared to Placebo in Adult Subjects With Active Systemic Lupus Erythematosus

Identification of Predictors for Clinical Outcomes in Femoroacetabular Impingement Surgery

Testing the Addition of an Anti-cancer Immune Therapy Drug (Nivolumab) to the Usual Chemotherapy Treatment (Cisplatin or Carboplatin With Gemcitabine) for Recurrent or Metastatic Nasopharyngeal Cancer

MB-105 in Patients With CD5 Positive T-cell Lymphoma

A Study to Evaluate Impact of Efanesoctocog Alfa on Long-term Joint Health in Participants With Hemophilia A

A Study to Evaluate ENERGI-F703 GEL in Diabetic Foot Ulcer

A Study to Learn About The COVID-19 (Study) Vaccine (Called COMIRNATY) in People That Are Less Than 21 Years Old.

Multi-Center Molecular Diagnosis and Host Response of Respiratory Viral Infections in Pediatric Transplant Recipients

A Study of Lenvatinib (MK-7902) in Pediatric Participants With Relapsed or Refractory Solid Malignancies (MK-7902-013/E7080)

A Study of AC676 for the Treatment of Relapsed/Refractory B-Cell Malignancies

A Study of Ponatinib With Chemotherapy in Children, Teenagers, and Adults With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

Expanded Access Protocol for Patients With Eosinophilic Esophagitis

LMWH vs Aspirin for VTE Prophylaxis in Orthopaedic Oncology

Immunogenicity, Safety, and Tolerability of rF1V-1018 Vaccine in Adults 18 to 55 Years of Age

Close Assessment and Testing for Chronic Graft Versus Host Disease, CATCH Study

Hyperbaric Oxygen Brain Injury Treatment Trial

Treating Pulmonary Embolism With Laguna Thrombectomy System (TRUST)