Clinical Trials in Atlanta

Showing 14521-14540 of 19,805 trials

Neural Circuits in Women With Abuse and Posttraumatic Stress Disorder

NCT01681849

The purpose of this study was to assess the effects of the medication paroxetine on symptoms of posttraumatic stress disorder (PTSD) and the brain in women with a history of PTSD related to childhood abuse. The hypothesis is that paroxetine will result in an improvement in PTSD symptoms accompanied by changes in brain functional response to reminders of childhood trauma.

PTSD

Emory University91 participantsStarted Jul 2009

Atlanta, Georgia, United States

COMPLETEDPhase 2/3< 1 mile

Evaluation of Sarilumab (SAR153191/REGN88) on Top of Methotrexate in Rheumatoid Arthritis Patients

NCT01061736

Primary Objectives: Part A (dose ranging study): To demonstrate that sarilumab (SAR153191/REGN88) on top of MTX was effective on reduction of signs and symptoms of rheumatoid arthritis at 12 weeks. Part B (pivotal study): To demonstrate that sarilumab added to MTX was effective in: * reduction of signs and symptoms of rheumatoid arthritis at 24 weeks * inhibition of progression of structural damage at 52 weeks * improvement in physical function at 16 weeks Secondary Objectives: Part B: To demonstrate that sarilumab added to MTX was effective in induction of a major clinical response at 52 weeks To assess the safety of sarilumab added to MTX To document the pharmacokinetic profile of sarilumab added to MTX in participants with active rheumatoid arthritis who were inadequate responders to MTX therapy.

Rheumatoid Arthritis

Sanofi1,675 participantsStarted Mar 2010

Anniston, Alabama, United States • Birmingham, Alabama, United States • Gilbert, Arizona, United States +259 more locations

Neural Circuits in Women With Abuse and Posttraumatic Stress Disorder

Evaluation of Sarilumab (SAR153191/REGN88) on Top of Methotrexate in Rheumatoid Arthritis Patients

Find Trials by Condition in Atlanta

S0800, Nab-Paclitaxel, Doxorubicin, Cyclophosphamide, and Pegfilgrastim With or Without Bevacizumab in Treating Women With Inflammatory or Locally Advanced Breast Cancer

Efficacy and Safety of Oral Rigosertib in Transfusion-dependent, Low or Int-1 or Trisomy 8 Int-2 Myelodysplastic Syndrome

Improving Patient Education for Lymphoma and Leukemia Inpatients

Collection of Patient-Reported Symptoms and Performance Status Via the Internet

To Study Generic Clindamycin 1%/Benzoyl Peroxide 5% Topical Gel (Glenmark Generics, Ltd) in the Treatment of Acne Vulgaris.

Cetuximab + / - Carboplatin for Estrogen Receptor-Negative, Progesterone Receptor-Negative Metastatic Breast Cancer

A Study of TRU-016 in Combination With Rituximab and Bendamustine in Subjects With Relapsed Indolent Lymphoma

A Study of MM-111 and Paclitaxel With Trastuzumab in Patients HER2 Positive Carcinomas of the Distal Esophagus, Gastroesophageal (GE) Junction and Stomach

To Evaluate The Safety of SAR153191 (REGN88) and Tocilizumab Added to Other RA Drugs in Patients With RA Who Are Not Responding to or Intolerant of Anti-TNF Therapy (SARIL-RA-ASCERTAIN)

Safety Study of the Ventricular Partitioning Device (VPD) Implant System in Heart Failure Patients

Literacy-Adapted Psychosocial Treatments for Chronic Pain --- "Learning About Mastering/My Pain"

Study of Voreloxin (Vosaroxin) in Older Patients With Untreated Acute Myeloid Leukemia

To Evaluate the Immunogenicity and Safety of Sarilumab Administered as Monotherapy in Patients With Rheumatoid Arthritis (RA)

Study of Tissue Samples From Patients With Non-Small Cell Lung Cancer

Impact of SBI, a Medical Food, on Nutritional Status in Patients With HIV-associated Enteropathy

Phase II Study to Analyze Sarilumab in Non-Infectious Uveitis

Evaluating Processes of Care & the Outcomes of Children in Hospital (EPOCH)

A First Time in Human Study to Assess GSK2336805 in Healthy Volunteers and Single Doses in Chronically Infected Hepatitis C Patients.