Clinical Trials in Atlanta

Showing 381-400 of 16,968 trials

PD, PK, and Safety of ALTO-203 in Patients With MDD

NCT06391593

The goal of this clinical trial is to determine the pharmacodynamic effects of ALTO-203 in patients with MDD in a randomized, placebo-controlled, single-dose crossover treatment period. Additionally, safety, tolerability, and PK will be assessed in a subsequent randomized placebo-controlled multi-dose parallel-group treatment period of 28 days. Participants will complete subjective response questionnaires and perform cognitive tasks during the single-dose period, in which participants will receive ALTO-203 25 μg and 75 μg, as well as placebo. During the multiple-dose period, participants will receive either ALTO-203 25 μg, 75 μg , or placebo. Safety will be assessed over the single dose and 28-day multiple dose periods.

Major Depressive DisorderAnhedonia

Alto Neuroscience69 participantsStarted Mar 2024

Tucson, Arizona, United States • Oceanside, California, United States • Torrance, California, United States +12 more locations

Not Yet RecruitingNA< 1 mile

Integrating Supports to Promote PrEP for Black Adolescents Working With Apps- Atlanta

NCT07535346

This study applies Social Cognitive Theory to develop behavioral interventions promoting PrEP adherence. It seeks to adapt and test the enhanced HMP app for feasibility and acceptability among Black adolescents and young adults (AYAs) and adult supports.

HIV Infections

Emory University10 participantsStarted Aug 2026

Atlanta, Georgia, United States

PD, PK, and Safety of ALTO-203 in Patients With MDD

Integrating Supports to Promote PrEP for Black Adolescents Working With Apps- Atlanta

Find Trials by Condition in Atlanta

Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)

ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study)

A Study of Selpercatinib (LOXO-292) in Participants With Advanced Solid Tumors, RET Fusion-Positive Solid Tumors, and Medullary Thyroid Cancer (LIBRETTO-001)

Trial to Evaluate the Immunogenicity of Dose Reduction Strategies of the MVA-BN Monkeypox Vaccine

Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 1

A Study to Assess the Safety, Pharmacokinetics, and Activity of RO7790121 in Participants With Advanced MASH Liver Fibrosis

A Study of CX11 Tablets in Patients With Type 2 Diabetes Mellitus

Study to Assess the Effects of Angiopoietin-like Protein 3 (ANGPTL3) Inhibition in Adult Participants With Diabetic Kidney Disease

Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer

Study of GS-9911 With or Without Antibody Treatment for Adults With Solid Tumors

The Willow LTE Study With M5049 in Participants With SCLE, DLE and/or SLE (WILLOW LTE)

A Study to Investigate the Pharmacokinetics of Tirabrutinib in Participants With Mild, Moderate, and Severe Hepatic Impairment Compared to Healthy Participants

A Study of Inlexisertib (DCC-3116) in Combination With Anticancer Therapies in Participants With Advanced Malignancies

MeSenteric SpAring Versus High Ligation Ileocolic Resection for the Prevention of REcurrent Crohn's DiseaSe (SPARES)

Phase II Study of Second- Line Pembrolizumab Plus GVD for Relapsed or Refractory Hodgkin Lymphoma

Use of the CA 125 Algorithm for the Early Detection of Ovarian Cancer in Low Risk Women

A Study of KIVU-107 in Participants With Locally Advanced or Metastatic Solid Tumors

Pharmacogenomics for Better Treatment of Fungal Infections Clinical Trial