Clinical Trials in Arizona

Showing 4901-4920 of 16,770 trials

Oral Administration of STC-15 in Subjects With Advanced Malignancies

NCT05584111

This Phase 1, multi-center, open-label, first-in-human study evaluates multiple ascending daily oral doses of STC-15 in Q3W treatment cycles in a 3+3 cohort design with dose levels determined by a modified Fibonacci algorithm. The study is designed to systematically assess safety and tolerability, pharmacokinetics, pharmacodynamics and clinical activity of STC-15 in adult subjects with advanced malignancies. Dose levels for further evaluation in expansion cohorts will be selected based on all available PK, pharmacodynamic, target engagement, efficacy, safety, and tolerability data including long-term safety data beyond dose limiting toxicities (DLTs). The study may be amended to evaluate STC-15 in combination with a Food and Drug Administration-approved standard of care treatment regimen, which could encompass targeted/chemotherapy, radiation therapy and/or immunotherapy with immune checkpoint blockers.

Advanced CancerAdvanced Solid TumorCancer

STORM Therapeutics LTD42 participantsStarted Nov 2022

Scottsdale, Arizona, United States • Houston, Texas, United States • San Antonio, Texas, United States

COMPLETEDNA33 miles

Safety and Efficacy of the SurVeil™ Drug-Coated Balloon

NCT03241459

To demonstrate the safety and efficacy of the SurVeil Drug-Coated Balloon (DCB) for treatment of subjects with symptomatic peripheral artery disease (PAD) due to stenosis of the femoral and/or popliteal arteries.

Peripheral Arterial DiseasePeripheral Vascular DiseaseArtery Disease, Peripheral+1 more

SurModics, Inc.446 participantsStarted Oct 2017

Birmingham, Alabama, United States • Foley, Alabama, United States • Gilbert, Arizona, United States +60 more locations

Oral Administration of STC-15 in Subjects With Advanced Malignancies

Safety and Efficacy of the SurVeil™ Drug-Coated Balloon

Find Trials by Condition in Arizona

MIP Versus PCNL for Kidney Stone Disease

A Study to Evaluate the Efficacy and Safety of Oral Zavegepant in Migraine Prevention

Phase 2 Trial of Voyager V1 in Combination With Cemiplimab in Cancer Patients

Efficacy Against Oral Persistent Infection, Immunogenicity and Safety of the 9-valent Human Papillomavirus Vaccine (9vHPV) in Men Aged 20-45 Years (V503-049)

Safety and Efficacy of BHV-3000 (Rimegepant) Orally Disintegrating Tablet for the Acute Treatment of Chronic Rhinosinusitis

Outcomes of a Skill-Based Program for Eating Disorders

Efficacy and Safety Study of Narsoplimab in Pediatric Patients With High-Risk Hematopoietic Stem Cell Transplant TMA

PArtial REbreathing for Migraine With Aura 1

Phase 1/2 Study of OBI-999 in Patients With Advanced Solid Tumors

A Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of Co-Administration of Roluperidone and Olanzapine in Adult Subjects With Moderate to Severe Negative Symptoms of Schizophrenia

Ibrutinib and Brentuximab Vedotin in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma

Study of NIS793 and Other Novel Investigational Combinations With SOC Anti-cancer Therapy for the 2L Treatment of mCRC

Optimal Post Tpa-Iv Monitoring in Ischemic Stroke

BURAN: Benralizumab on Airway Dynamics in Severe Eosinophilic Asthma Using Functional Respiratory Imaging

A Prospective Observational Study of TPIAT

A Trial of Pembrolizumab in Combination With Chemotherapy and Radiotherapy in Stage III NSCLC (KEYNOTE-799, MK-3475-799)

Kids FACE FEARS Comparative Effectiveness Research

Urine CXCL10 Monitoring Trial in Kidney Transplant