Clinical Trials in Arizona

Showing 4521-4540 of 16,770 trials

SPIROMICS Study of Early COPD Progression (SOURCE)

NCT05033990

This is an observational study of 1000 participants to further define the nature of early chronic obstructive pulmonary disease (COPD) in younger, at-risk individuals. The study has three main goals: * To use CT scan imaging to identify which smokers will develop COPD. * To identify biomarkers predictive of smokers that will develop COPD. * To determine if sputum (phlegm) can be analyzed to predict which smokers will develop COPD. Procedures (methods): All participants will undergo study related questionnaires assessing medical history, smoke exposure and use, medication use, social and behavioral health, pulmonary symptoms, food frequency, and will provide nasal swab, blood, stool, and urine samples, pulmonary function testing to determine function, sputum induction to provide a sputum sample for airway biospecimen analysis, and CT imaging of the lungs.

COPD, Early-Onset

University of Massachusetts, Worcester1,000 participantsStarted Sep 2021

Birmingham, Alabama, United States • Scottsdale, Arizona, United States • Los Angeles, California, United States +11 more locations

COMPLETEDPhase 135 miles

A Drug-Drug Interaction Study of Carbamazepine and Opevesostat (MK-5684) in Healthy Adult Male Participants (MK-5684-012)

NCT06633419

Researchers have designed a study medicine called opevesostat as a new way to treat prostate cancer. The purpose of this study is to learn what happens to opevesostat in a person's body over time (a pharmacokinetic or PK study). Researchers will compare what happens to opevesostat in the body when it is given with and without another medicine called carbamazepine.

Healthy

Merck Sharp & Dohme LLC14 participantsStarted Dec 2024

Tempe, Arizona, United States

SPIROMICS Study of Early COPD Progression (SOURCE)

A Drug-Drug Interaction Study of Carbamazepine and Opevesostat (MK-5684) in Healthy Adult Male Participants (MK-5684-012)

Find Trials by Condition in Arizona

Randomized Therapy In Status Epilepticus

Evaluating SUI-100™, A Non-Invasive Device for the Treatment of Stress Urinary Incontinence

SportsPro: Post-Market Clinical Follow Up Study

Flexiva Pulse Registry

Modifiers of Disease Severity in Cerebral Cavernous Malformations

Intravenous Iloprost in Subjects With Symptomatic Raynaud's Phenomenon Secondary to Systemic Sclerosis (Phase 2)

Ruxolitinib Phosphate, Paclitaxel, and Carboplatin in Treating Patients With Stage III-IV Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

A Study to Investigate Efficacy and Safety of OG-6219 BID in 3 Dose Levels Compared With Placebo in Participants Aged 18 to 49 With Moderate to Severe Endometriosis-related Pain

A Study of the Efficacy and Safety of Frespaciguat (MK-5475) in Participants With Pulmonary Arterial Hypertension (INSIGNIA-PAH: Phase 2/3 Study of an Inhaled sGC Stimulator in PAH) (MK-5475-007)

A Safety and Immune Response Study to Evaluate Varying Doses of an mRNA Vaccine Against Coronavirus Disease 2019 (COVID-19) in Healthy Adults

Safety and Tolerability of M254 in Healthy Volunteers and Immune Thrombocytopenic Purpura (ITP) Patients

Safety and Efficacy of Tideglusib in Congenital or Childhood Onset Myotonic Dystrophy

Compound 31543 (Calcitriol, USP) in Patients Receiving Taxane-based Chemotherapy Regimens for the Treatment of Chemotherapy-Induced Alopecia

A Safety Study of RTA 744 in Patients With Recurrent High-Grade Gliomas

A Monotherapy in Subjects With Advanced Solid Tumors

A Study of CAP-1002 in Ambulatory and Non-Ambulatory Patients With Duchenne Muscular Dystrophy

A Study on How NNC0174-1213 Works in People With Overweight or Obesity.

Study With Gemcitabine and RTA 402 for Patients With Unresectable Pancreatic Cancer