Ulcerative Colitis Clinical Trials

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Hyperalgesia in Methadone-Maintained Patients: Can it be Treated?

NCT01210079

Utilizing a double-blind, placebo-controlled design, the proposed work will evaluate the ability of an adjuvant anticonvulsant analgesic to diminish or reverse the opioid-induced hyperalgesia complicating the pain states suffered by Methadone-Maintained (MM) patients. Specifically, in a sample of MM patients, gabapentin, which has proven efficacy in treating neuropathic pain will be evaluated for its ability to ameliorate or diminish the opioid-induced hyperalgesia in these patients as reflected by changes on pain threshold and tolerance to both cold-pressor and electrical pain, at peak and through methadone blood levels. The results of this work will not only provide pharmacologic insight into the mechanisms underlying poor pain tolerance in this at-risk population, but also direction for the medical management of pain complicated by opioid-induced hyperalgesia.

Opioid-Induced Hyperalgesia

University of California, Los Angeles26 participantsStarted Sep 2002

Los Angeles, California, United States

COMPLETEDPhase 3

Efficacy Study of Travoprost APS Versus TRAVATAN

NCT00848536

A Multi-Center Double-masked Study of the Safety and Efficacy of Travoprost APS Compared to TRAVATAN in Patients with Open-angle Glaucoma or Ocular Hypertension

Open Angle GlaucomaOcular Hypertension

Alcon Research371 participantsStarted Mar 2009

UNKNOWNNA

Clinical Hypnosis During Insemination or Embryotransfer

NCT01567241

Does clinical hypnosis or relaxation music improve the pregnancy rate if reproduction techniques are required?

Reproduction Dysfunction

Johann Wolfgang Goethe University Hospital282 participantsStarted Mar 2012

Frankfurt am Main, Hesse, Germany

Hyperalgesia in Methadone-Maintained Patients: Can it be Treated?

Efficacy Study of Travoprost APS Versus TRAVATAN

Clinical Hypnosis During Insemination or Embryotransfer

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