Ulcerative Colitis Clinical Trials

Showing 6241-6260 of 9,572 trials

CI-AKI in Patients With Stable CAD and Comorbidities. Are we Doing Better?

NCT04014153

Patients aged 18-89 with stable CAD and comorbidities receiving optimal medical treatment requiring PCI with iodinated contrast media. The aim of the study is to assess the prevalence of contrast-induced AKI in 2012-2013 and 2017 cohorts and to evaluate the potential risk factors of CI-AKI to better guide the prevention in patients of higher risk.

Stable AnginaAcute Kidney InjuryContrast-induced Nephropathy

I.M. Sechenov First Moscow State Medical University1,023 participantsStarted May 2012

COMPLETEDPhase 2

Mitochondria and Chronic Kidney Disease

NCT03177798

The overarching goal of this study is to determine the role of chronic kidney disease and the activation of the kallikrein-kinin system during hemodialysis on the development of mitochondrial dysfunction; the investigators will measure mitochondrial function using the gold standard method, 31-phosphorus magnetic resonance spectroscopy. The investigators will test the hypothesis that endogenous bradykinin promotes mitochondrial dysfunction in patients undergoing hemodialysis. The investigators will first perform a randomized, placebo-controlled, double-blind, cross-over study measuring the effect of Icatibant (HOE-140), a bradykinin B2 receptor blocker, on mitochondrial function.

Hemodialysis-Induced SymptomMitochondrial Diseases

Vanderbilt University Medical Center11 participantsStarted Aug 2017

Nashville, Tennessee, United States

CI-AKI in Patients With Stable CAD and Comorbidities. Are we Doing Better?

Mitochondria and Chronic Kidney Disease

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