Schizophrenia Clinical Trials

Showing 1001-1020 of 1,172 trials

Effect of Genotyping for CYP450 Polymorphisms Versus Intense Clinical Monitoring on Antipsychotic Drug Treatment

NCT00707382

The purpose of this study is to determine whether genotyping for CYP2D6 and 2C19 polymorphisms or intense clinical monitoring of treatment and adverse effects improves the antipsychotic treatment in patients with schizophrenia. This study is designed as a three-armed prospective randomized controlled clinical trial and includes 300 patients with schizophrenia. Patients are followed for a period of one year. During the study period the following effect measures are registered: * Time to discontinuation of all antipsychotic medications * Number of changes in medication dose * Number of changes in medication * Compliance (patients´ adherence to medical treatment) * Clinical symptoms * Adverse effects

Schizophrenia

Gesche Jurgens311 participantsStarted Feb 2008

Copenhagen, Denmark

COMPLETEDPhase 1

Effects of Cariprazine on Cardiac Repolarization in Patients With Schizophrenia

NCT01376076

This study will evaluate the effects of sequential multiple dose regimens of cariprazine on cardiac repolarization in patients with schizophrenia.

Schizophrenia

Forest Laboratories129 participantsStarted Jun 2011

Glendale, California, United States • Long Beach, California, United States • Willingboro, New Jersey, United States +1 more locations

Effect of Genotyping for CYP450 Polymorphisms Versus Intense Clinical Monitoring on Antipsychotic Drug Treatment

Effects of Cariprazine on Cardiac Repolarization in Patients With Schizophrenia

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