Rheumatoid Arthritis Clinical Trials in Philadelphia

Showing 1681-1700 of 3,347 trials

Bicycle Exercise Echocardiography to Assess Physiological Significance of Mitral Annular Calcification

NCT04093973

Many people develop calcium deposits in the heart as they get older. One of the common places for this to occur is the mitral annulus, the band of tissue that supports the mitral valve (one of four heart valves). The purpose of this study is to examine effects of these deposits (termed mitral annular calcification or "MAC") on a person's ability to perform exercise. The research team will use ultrasound of the heart (Doppler echocardiography) to study people with MAC while they exercise on a specially designed bicycle.

Mitral Annulus Calcification

Albert Einstein Healthcare Network40 participantsStarted Nov 2014

Philadelphia, Pennsylvania, United States

TERMINATEDPhase 3< 1 mile

Comparing NUC-1031 Plus Cisplatin to Gemcitabine Plus Cisplatin in Patients With Advanced Biliary Tract Cancer

NCT04163900

NuTide:121 compares NUC-1031 with gemcitabine, both in combination with cisplatin, in patients with previously untreated advanced biliary tract cancer. The primary hypotheses are: * The combination of NUC-1031 plus cisplatin prolongs overall survival compared to the gemcitabine plus cisplatin standard of care * The combination of NUC-1031 plus cisplatin increases overall response rate compared to the gemcitabine plus cisplatin standard of care

Biliary Tract Cancer

NuCana plc773 participantsStarted Dec 2019

Tucson, Arizona, United States • Tucson, Arizona, United States • Whittier, California, United States +122 more locations

Bicycle Exercise Echocardiography to Assess Physiological Significance of Mitral Annular Calcification

Comparing NUC-1031 Plus Cisplatin to Gemcitabine Plus Cisplatin in Patients With Advanced Biliary Tract Cancer

Rheumatoid Arthritis Trials in Other Cities

Open-Label Study of Leuco-methylthioninium Bis(Hydromethanesulfonate) (LMTM) in Subjects With Alzheimer's Disease or Behavioral Variant Frontotemporal Dementia (bvFTD)

Confocal Endomicroscopy for Improved Diagnosis of Barrett's Esophagus and Early Esophageal Cancer(CEBE Study)

Accelerated TMS to a Novel Brain Target in MDD and PTSD

Randomized Trial in Adult Participants With Acute Migraines

Relative Bioavailability of LY03010 Compared to Listed Drug

A Phase 4 Study of Efficacy and Safety of Apremilast in Subjects With Moderate Plaque Psoriasis.

rhBMP-2/CRM/CD HORIZON® Spinal System Pivotal Study

Therapeutic Endoscopic Ultrasound for Gastrointestinal Disorders: A Multicenter Registry Study

Salsalate, Venetoclax, and Decitabine or Azacitidine for the Treatment of Acute Myeloid Leukemia or Advanced Myelodysplasia/Myeloproliferative Disease

AllyQuest Adherence App Intervention for HIV-positive Men Who Have Sex With Men and Transgender Women: Pilot Trial

Efficacy and Safety of NYX-2925 in Subjects With Neuropathic Pain Associated With Diabetic Peripheral Neuropathy (DPN)

Pilot Bi-Lateral Tubal Occlusion Trial for Female Permanent Contraception

Thrombosomes® in Bleeding Thrombocytopenic Patients Study

A Study to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple- Dose BIVV009 in Participants With Chronic Immune Thrombocytopenia (ITP)

MK-7625A Plus Metronidazole Versus Meropenem in Pediatric Participants With Complicated Intra-Abdominal Infection (cIAI) (MK-7625A-035)

MK-7625A Versus Meropenem in Pediatric Participants With Complicated Urinary Tract Infection (cUTI) (MK-7625A-034)

Single-Ascending Dose Study of JK07 in Subjects With HFpEF

First-In-Human Study To Evaluate Safety, Tolerability, And Pharmacokinetics Following Single Ascending And Multiple Ascending Doses of PF-07304814 In Hospitalized Participants With COVID-19.

Other Conditions in Philadelphia