Rheumatoid Arthritis Clinical Trials in Philadelphia

Showing 1121-1140 of 3,347 trials

Window of Opportunity Trial of Nivolumab and Tadalafil in Patients With Squamous Cell Carcinoma of the Head and Neck

NCT03238365

This randomized pilot early phase I trial studies how well nivolumab with or without tadalafil work in treating patients with head and neck squamous cell carcinoma that has come back and can be removed by surgery. Monoclonal antibodies, such as nivolumab, may interfere with the ability of tumor cells to grow and spread. Tadalafil may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving nivolumab and tadalafil may work better in treating patients head and neck squamous cell carcinoma.

Lip, Oral Cavity and PharynxLarynx

Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University50 participantsStarted Aug 2017

Philadelphia, Pennsylvania, United States • Nashville, Tennessee, United States

COMPLETED< 1 mile

Linking Endotypes and Outcomes in Pediatric Acute Respiratory Distress Syndrome

NCT04113434

The overall goal of the study is to risk stratify pediatric Acute Respiratory Distress Syndrome (ARDS) patients and to identify sub-phenotypes with shared biology in order to appropriately target therapies in future trials. This is a prospective, multicenter study of 500 intubated children with ARDS, with planned blood collection within 24 hours of ARDS onset and subsequent measurement of plasma protein biomarkers and peripheral blood gene expression.

Acute Respiratory Distress Syndrome

Children's Hospital of Philadelphia500 participantsStarted Jan 2020

Little Rock, Arkansas, United States • Aurora, Colorado, United States • Miami, Florida, United States +13 more locations

Window of Opportunity Trial of Nivolumab and Tadalafil in Patients With Squamous Cell Carcinoma of the Head and Neck

Linking Endotypes and Outcomes in Pediatric Acute Respiratory Distress Syndrome

Rheumatoid Arthritis Trials in Other Cities

Reduced Intensity Chemotherapy and Radiation Therapy Before Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Traumatic Hemothorax Drainage and Daily Lavage: Pilot Study

A Study of Venoarterial ECMO vs Off-Pump Bilateral Orthotopic Lung Transplantation

A Study to Evaluate Rozanolixizumab in Study Participants With Generalized Myasthenia Gravis

Extracorporeal Photopheresis for Medicare Recipients of Lung Allografts

Neuromotor Prosthetic to Treat Stroke-Related Paresis

Phase 2 Study of HL-009 Liposomal Gel to Treat Mild to Moderate Atopic Dermatitis

A Study of CTX-009 in Combination With Paclitaxel in Adult Patients With Unresectable Advanced, Metastatic or Recurrent Biliary Tract Cancers (COMPANION-002)

Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (Ocular Therapeutix) (Axitinib Implant) in Subjects With Neovascular Age-Related Macular Degeneration

DALY II USA/ MB-CART2019.1 for DLBCL

Laser Ablation of Abnormal Neurological Tissue Using Robotic NeuroBlate System

Comparative Study of Conventional MR Images With Synthetically Reconstructed MR Images of the Brain

Study of REM-422 in Patients With AML or Higher Risk MDS

Visualization of the STN and GPi for DBS

Prophylaxis and Treatment of COVID-19

Clinical Trial Readiness to Solve Barriers to Drug Development in FSHD

Open-Label Extension: Tolerability and Effects of ALK-001 on Stargardt Disease (TEASE)

Phase 2b Study of MBS2320 in Participants With Methotrexate-Refractory RA

Other Conditions in Philadelphia