Psoriasis Clinical Trials in Philadelphia

Showing 101-120 of 192 trials

Single and Multiple Dose Escalation Study to Assess the Safety and Tolerability of CJM112 in Psoriasis

NCT01828086

A randomized, double-blind, placebo and positive controlled, single and multiple dose study to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of CJM112 in chronic plaque-type psoriasis patients. This trial never made it to the Phase II part of this trial.

Chronic Plaque-type Psoriasis

Novartis Pharmaceuticals95 participantsStarted Jun 2013

Anniston, Alabama, United States • Anaheim, California, United States • Encino, California, United States +15 more locations

COMPLETED< 1 mile

PET/CT in Psoriatic Arthritis

NCT01654198

When patients with psoriasis develop joint pain, it is often hard to decide whether or not the pain is due to psoriatic arthritis (PsA). At this time, doctors use information from the history and physical exam to determine the diagnosis. X-rays, magnetic resonance imaging (MRI) and ultrasound have been used to help with the diagnosis but all three have limitations. A newer imaging technique, whole body Positron Emission Tomography/Computed Tomography (PET/CT) uses the idea that inflammatory cells take up sugar to locate inflammation in the body. Because patients with PsA have inflammatory cells in their joints and tendons, this type of scan allows the physician to take a picture of the whole body and locate inflammation. The investigators have found that some patients with psoriasis (but without arthritis) have inflammation in joints and tendons even before the patient has symptoms. In this study, the investigators will explore how well PET/CT works for assessing inflammation in patients with PsA. This would be a very exciting tool that could be used to find and treat inflammation before it causes damage or pain.

Psoriatic Arthritis

University of Pennsylvania12 participantsStarted Jul 2012

Philadelphia, Pennsylvania, United States

Single and Multiple Dose Escalation Study to Assess the Safety and Tolerability of CJM112 in Psoriasis

PET/CT in Psoriatic Arthritis

Psoriasis Trials in Other Cities

Psoriasis Microbiome and Phototherapy

A Study of Ixekizumab (LY2439821) Compared to Guselkumab in Participants With Moderate-to-Severe Plaque Psoriasis

A Study Comparing Different Dosing Regimens of Ixekizumab (LY2439821) in Participants With Moderate to Severe Plaque Psoriasis

A Study to Assess Safety and Efficacy of Risankizumab Using a New Formulation in Participants With Moderate to Severe Plaque Psoriasis

Safety and Efficacy of IDP-118 in the Treatment of Plaque Psoriasis

LEO 90100 Twice Weekly Maintenance Regimen for Psoriasis Vulgaris

A Study of the Efficacy and Safety of Apremilast (CC-10004) in Subjects With Moderate to Severe Plaque Psoriasis of the Scalp

Study to Evaluate the Efficacy of Etanercept Treatment in Adults Who Failed Therapy With Apremilast

Efficacy and Safety Study of Apremilast to Treat Active Psoriatic Arthritis

Investigate Effect of Secukinumab on the PK of Midazolam in Patients With Mod to Sev Plaque Psoriasis

Brodalumab in Subjects With Moderate to Severe Plaque Psoriasis Who Have Failed IL-17A Therapies

To Study Generic Calcipotriene and Betamethasone Dipropionate Topical Foam, 0.005%/0.064%, in the Treatment of Psoriasis Vulgaris (Plaque Psoriasis).

Study of Efficacy and Safety of Brodalumab in Subjects With Psoriatic Arthritis

AMG 827 in Subjects With Psoriatic Arthritis

A Dose Finding Study of AEB071 Assessing Psoriasis Area and Severity Index in Patients With Plaque Psoriasis

Topical CP-690,550 For Chronic Plaque Psoriasis

A Study to Evaluate the Safety, Pharmacokinetics, and Efficacy of Topical ESR-114 in Subjects With Plaque Psoriasis

CP-690-550 Ointment For Chronic Plaque Psoriasis

Other Conditions in Philadelphia