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Clareo Health | Pancreatic Cancer Clinical Trials in Philadelphia | 250 Studies

Clinical Trials Pancreatic CancerPhiladelphia

Pancreatic Cancer Clinical Trials in Philadelphia

Find 250 clinical trials for pancreatic cancer near Philadelphia, Pennsylvania. Connect with research centers in your area.

All Pancreatic Cancer trials nationwide All trials in Philadelphia

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 21-40 of 250 trials

Active not recruitingA Study of ELI-002 7P in Subjects With KRAS/NRAS Mutated Solid TumorsThis is a Phase 1/2 study to assess the safety and efficacy of ELI-002 7P immunotherapy (a lipid-conjugated immune-stimulatory oligonucleotide \[Amph-CpG-7909\] plus a mixture of…NCT05726864·Gilbert, Arizona and 27 others Approved for marketingExpanded Access for the Treatment of Cancers With Rearranged During Transfection (RET) ActivationExpanded access for participants with cancer with RET activation who are ineligible for an ongoing selpercatinib (also known as LOXO-292) clinical trial or have other…NCT03906331·Goodyear, Arizona and 63 others

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Data from ClinicalTrials.govTerms

WithdrawnA Study of Fractionated 90Y-hPAM4 Plus Gemcitabine in Pancreatic Cancer Patients Receiving at Least 2 Prior Therapies.90Y-hPAM4 is administered weekly for 3 weeks combined with 4 weekly doses of gemcitabine to assess.NCT01510561·Gilbert, Arizona and 23 others

CompletedGemcitabine With or Without Oxaliplatin in Treating Patients With Locally Advanced or Metastatic Pancreatic CancerRATIONALE: Drugs used in chemotherapy such as gemcitabine and oxaliplatin use different ways to stop tumor cells from dividing so they stop growing or die.NCT00058149·Huntsville, Alabama and 60 others

CompletedNiraparib + Ipilimumab or Nivolumab in Progression Free Pancreatic Adenocarcinoma After Platinum-Based ChemotherapyThe main purpose of this study is to look at the effectiveness, safety, and anti-tumor activity (preventing growth of the tumor) of the drugs Niraparib with either Ipilimumab or…NCT03404960·Philadelphia, Pennsylvania

Active not recruitingPhase 3 Study of Daraxonrasib (RMC-6236) in Patients With Previously Treated Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)The purpose of this study is to evaluate the safety and efficacy of a novel RAS(ON) inhibitor compared to standard(s) of care (SOC) treatment.NCT06625320·Gilbert, Arizona and 59 others

TerminatedParicalcitol Plus Gemcitabine and Nab-paclitaxel in Metastatic Pancreatic CancerThis research study is a two stage study which consists of a safety run-in phase and a randomized phase 2 study which include subjects with previously-untreated, metastatic…NCT03520790·Boston, Massachusetts and 1 other

CompletedA Study of XmAb®23104 in Subjects With Selected Advanced Solid Tumors (DUET-3)This is a Phase 1, multiple dose, ascending dose escalation study to define a MTD/RD and regimen of XmAb23104, to describe safety and tolerability, to assess PK and…NCT03752398·San Diego, California and 17 others

TerminatedEfficacy and Safety of BC-819 and Gemcitabine in Patients With Locally Advanced Pancreatic AdenocarcinomaThis is a multicenter, open label, randomized, phase 2b study, designed to evaluate the safety and efficacy of patients with locally advanced pancreatic adenocarcinoma following…NCT01413087·Mineola, New York and 8 others

CompletedBevacizumab, Combination Chemotherapy, and Radiation Therapy in Treating Patients Undergoing Surgery For Locally Advanced Pancreatic CancerRATIONALE: Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread.NCT00602602·Philadelphia, Pennsylvania

CompletedSafety and Efficacy Study of 90Y-hPAM4 at Different DosesSafety study to determine highest dose of 90Y-hPAM4 can be safety administeredNCT00597129·Goshen, Indiana and 3 others

CompletedSafety Study of Nivolumab With Nab-Paclitaxel Plus or Minus Gemcitabine in Pancreatic Cancer, Nab-Paclitaxel / Carboplatin in Stage IIIB/IV Non-Small Cell Lung Cancer or Nab-Paclitaxel in Recurrent Metastatic Breast CancerThe purpose of this study is to assess safety of nab-paclitaxel based chemotherapy regimens administered prior to and/or in combination with nivolumab in Pancreatic Cancer, Non…NCT02309177·Sacramento, California and 14 others

Active not recruitingCarcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine RegimenA Phase 3, randomized, double-blinded, placebo-controlled study to evaluate the efficacy and safety of paltusotine treatment vs placebo as well as the long-term safety of…NCT07087054·Gilbert, Arizona and 71 others

CompletedErlotinib, Gemcitabine and Nab-Paclitaxel in Advanced Pancreatic CancerThis is a phase 1b study to evaluate the combination of gemcitabine and Tarceva (erlotinib) and nab-paclitaxel in patients with advanced pancreatic cancer.NCT01010945·Palm Springs, California and 4 others

Active not recruitingA Phase I Dual Dose Escalation Study of Radiation and Nab-Paclitaxel in Patients With Unresectable and Borderline Resectable Pancreatic CancerThe investigators hypothesize that intensification of local therapy will lead to improvements in local control and survival in patients with unresectable and borderline resectable…NCT02207465·Philadelphia, Pennsylvania and 1 other

CompletedTrial to Improve Outcomes in Patients With Resected Pancreatic Cancer (Azacitidine)To improve progression free survival in high risk patients with resected pancreatic adenocarcinoma who have node positive disease, margin positive disease, and/or elevation in CA…NCT01845805·Baltimore, Maryland and 3 others

Active not recruitingStudy of DECOY20 With or Without Tislelizumab in Patients With Advanced Solid TumorsINDP-D101 is a Phase 1/2, open-label, multi-center, dose escalation and expansion study evaluating the safety, tolerability and clinical activity of Decoy20 as monotherapy and in…NCT05651022·Los Angeles, California and 11 others

TerminatedA Study of CART-TnMUC1 in Patients With TnMUC1-Positive Advanced CancersMulti-center, open-label, first in human Phase 1 study of the safety, tolerability, feasibility, and preliminary efficacy of the administration of genetically modified autologous…NCT04025216·Phoenix, Arizona and 9 others

RecruitingTCR1188-ABC Cells in KRAS-mutated CancersThis is a Phase I, open-label dose finding study to assess the safety, manufacturing feasibility, and preliminary efficacy of TCR1188-ABC cells in patients with KRAS-mutated…NCT07594067·Philadelphia, Pennsylvania

TerminatedHigh or Standard Intensity Radiation Therapy After Gemcitabine Hydrochloride and Nab-paclitaxel in Treating Patients With Pancreatic Cancer That Cannot Be Removed by SurgeryThis randomized phase II trial studies how well high or standard intensity radiochemotherapy after gemcitabine hydrochloride and paclitaxel albumin-stabilized nanoparticle…NCT01921751·Oakland, California and 45 others

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