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Browse 4,295 clinical trials for obesity. Find studies that match your criteria and connect with research centers.
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NCT07373795
The goal of this clinical trial is to learn if Maqui berry gummy encapsulated (GMM) compared to non-encapsulated (GM) can improve glycemic response in overweight adults. It will also learn about the possible effect of serum antioxidant levels. The main questions it aims to answer are: Does GMM or GM low the glycemic response in overweight/obese subjects after consuming a carbohydrate rich food? Does GMM or GM increase antioxidant levels in overweight/obese subjects after consuming a carbohydrate rich food? Researchers will compare (i) a carbohydrate rich food, (ii) GMM + a carbohydrate rich food, (iii) GM + a carbohydrate rich food to see if Maqui gummy work to control glycemic and antioxidant levels. Participants will: Take a carbohydrate rich food, and/or Maqui gummy three times, one week apart Have blood samples collected and answer food questionnaires in each visit
NCT06768827
Given the pervasiveness of Pediatric Obesity, it is imperative to understand its pathophysiology and develop alternative strategies to reverse this condition. Herein, investigators propose to elucidate the interaction between colonic fermentation and insulin resistance in modulating metabolism in youth with obesity.
NCT07216820
The goal of this clinical trial is to learn whether a phrenic-sparing nerve block can lower early breathing problems after shoulder surgery in adults with obesity, and whether a simple breathing-strength test (maximum inspiratory pressure, MIP) helps identify who is at higher risk. The main questions are: Does the phrenic-sparing approach reduce breathlessness or oxygen need in the recovery room (30-60 minutes after arrival)? Do patients have similar pain control and opioid use compared with the standard interscalene block (ISB)? Are there any breathing-related complications or unplanned admissions within 24 hours? Researchers will compare the phrenic-sparing block (infraclavicular + distal suprascapular) to the standard ISB, both commonly used at UNC. Participants will: Have a quick MIP breath test before surgery (and, if age ≥65, a brief thigh muscle ultrasound). Be randomly assigned to receive either the standard ISB or the phrenic-sparing block (both ultrasound-guided and part of routine care). Receive usual anesthesia/surgery; have a brief recovery check at 30-60 minutes (breathlessness score, oxygen use, oxygen level). Have pain medicines recorded from anesthesia start to PACU discharge; the team may review the chart up to 24 hours and make a short follow-up call (24-48 hours).