Multiple Sclerosis Clinical Trials

Showing 1181-1200 of 5,093 trials

Immunotherapy With Y90-RadioEmbolization for Metastatic Colorectal Cancer

NCT04108481

This clinical trial will be conducted as a single-center, open-label, Phase I/2 trial to evaluate the feasibility and safety of Yttrium-90 radioembolization (Y90-RE) in combination with a fixed dose of of immunotherapy (durvalumab - 750 mg) in subjects with liver-predominant, metastatic colorectal cancer (mCRC), which is mismatch repair proficient/microsatellite stable (pMMR/MSS).

Colorectal Cancer MetastaticColon CancerMetastatic Colorectal Cancer+7 more

University of Iowa5 participantsStarted Oct 2020

Iowa City, Iowa, United States

Enrolling By InvitationNA

Cluster RCT of Cognitive Behavioral Therapy to Support Caregivers of Older Adults in Hong Kong

NCT06473012

The goal of this cluster randomized controlled trial study is to compare the effectiveness of a novel psychosocial intervention based on Cognitive Behavioral Therapy, lifestyle intervention and effective communication skills in caregivers of older adults in Hong Kong. The main question\[s\] it aims to answer are: What is the impact of the 6-week psychosocial intervention on distress and burden among participants? Participants will participate in a 6-week psychosocial intervention. Researchers will compare the results between the intervention group and the active control group to see if participants in the intervention group have lower distress and burden.

Caregiver BurdenDepressive SymptomsQuality of Life+2 more

The University of Hong Kong250 participantsStarted Sep 2024

Hong Kong, Hong Kong

Immunotherapy With Y90-RadioEmbolization for Metastatic Colorectal Cancer

Cluster RCT of Cognitive Behavioral Therapy to Support Caregivers of Older Adults in Hong Kong

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Analysis of Exploring Optimized Sequential Treatment Strategies of Antibody-Drug Conjugates (ADCs) in HER2-Low-Expressing Breast Cancer

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Short-course Radiotherapy or Long-course Chemoradiation Followed by MFOLFOXIRI Consolidation Chemotherapy for Organ Preservation in Low Rectal Cancer

Applications of Ultrasound and Physical Parameters in Assessing Fall Risk in Patients With Knee Osteoarthritis

Effects of MS Ballroom Fitness on Balance, Walking Capacity, and Well-being in Multiple Sclerosis

Cadonilimab for PD-1/PD-L1 Blockade-refractory, MSI-H/dMMR, Advanced Colorectal Cancer

SBIR/ STTR Family Check-up Online

Investigation of Validity and Reliability of the Minnesota Manual Dexterity Test in Patients With Multiple Sclerosis

PRescription Exercise for Older Men With Urinary Disease

Effects of Chiropractic Care on Cytokine Levels in Multiple Sclerosis

Efficacy and Safety of Antiplatelet Therapy After Endovascular Aortic Repair