Melanoma Clinical Trials

Showing 61-80 of 1,292 trials

A Phase 1-1b Study to Evaluate the Safety, Efficacy and Dosimetry of Study Drug A9-3408 in Subjects With Metastatic Melanoma

NCT07076550

The goal of this trial is to see if this investigational drug is safe for adult patients with melanoma that has spread to other parts of the body or cannot be removed by surgery. It will also see if this investigational drug can shrink melanoma tumors in the body. The main questions this study aims to answer are: * What are the side effects of this investigational drug? * What is the highest dose of this investigational drug that can be given safely? Participants will: * Take the investigational drug once every 6 weeks, for up to 6 times in total * Visit a doctor's office on a regular basis for checkups and tests

Melanoma MetastaticUveal Melanoma, MetastaticMucosal Melanoma

Alpha-9 Oncology USA Inc.50 participantsStarted Nov 2025

Melbourne, Victoria, Australia • Melbourne, Victoria, Australia • Murdoch, Western Australia, Australia +1 more locations

Active Not RecruitingPhase 2

(Neo)Adjuvant IDE196 (Darovasertib) in Patients With Localized Ocular Melanoma

NCT05907954

Neoadjuvant/adjuvant IDE196 (darovasertib) in patients with primary uveal melanoma

Uveal Melanoma

IDEAYA Biosciences160 participantsStarted Jul 2023

Scottsdale, Arizona, United States • La Jolla, California, United States • Palo Alto, California, United States +15 more locations

A Phase 1-1b Study to Evaluate the Safety, Efficacy and Dosimetry of Study Drug A9-3408 in Subjects With Metastatic Melanoma

(Neo)Adjuvant IDE196 (Darovasertib) in Patients With Localized Ocular Melanoma

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VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3]

A Study of PF-08046049/SGN-BB228 in Advanced Melanoma and Other Solid Tumors

Study of AMXT 1501 and DFMO in Combination With Standard Therapies in Advanced Solid Tumors

Study of Efficacy and Safety of LXH254 Combinations in Patients With Previously Treated Unresectable or Metastatic Melanoma

Narrow Excision Versus Wide Excision for the Treatment of Adults With Invasive Cutaneous Melanoma, ICEMAN Trial

Evaluation of the Safety and Tolerability of i.v. Administration of a Cancer Vaccine in Patients With Advanced Melanoma

MC1R-targeted Alpha-particle Monotherapy and Combination Therapy Trial With Nivolumab in Adults With Advanced Melanoma

A Study Comparing 3 Study Medicines (Encorafenib, Binimetinib, Pembrolizumab) to 2 Study Medicines (Ipilimumab and Nivolumab) in Patients With Advanced Melanoma

Tocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial Carcinoma

Characterisation of T Lymphocytes, NK Cells and Macrophages in Melanoma Patients

STC-15 as a Part of Combination Therapy With Toripalimab in Selected Advanced Cancers

Consolidative Use of Radiotherapy to Block Oligoprogression in Patients With Metastatic Melanoma

Effects of Lavender Aromatherapy on Patient Anxiety During Mohs Micrographic Surgery

Study of DCC-3084 in Participants With Advanced Malignancies Driven by the Mitogen-Activated Protein Kinase (MAPK) Pathway

IKKb-matured, RNA-loaded Dendritic Cells for Metastasised Uveal Melanoma

RWS of Tunlametinib in NRAS-Mutant Advanced Melanoma

A Phase II Trial of LM103 in Advanced Melanoma

Psilocybin-Assisted Psychotherapy in Cancer Patients With Adjustment Disorder