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Clareo Health | Melanoma Clinical Trials in Houston | 429 Studies

Clinical Trials MelanomaHouston

Melanoma Clinical Trials in Houston

Find 429 clinical trials for melanoma near Houston, Texas. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Houston

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 101-120 of 429 trials

Active not recruitingA Study of JZP815 Oral Capsules in Adult Participants With Advanced or Metastatic Solid Tumors Harboring Mitogen Activated Protein Kinase (MAPK) Pathway Alterations to Investigate the Safety, Dosing, and Antitumor Activity of JZP815This phase 1 study will investigate the safety, dosing, and initial antitumor activity of JZP815 in participants with advanced or metastatic solid tumors harboring alterations in…NCT05557045·Los Angeles, California and 14 others TerminatedTreatment With Dasatinib in Patients With Acral Lentiginous, Mucosal, or Chronic Sun-damaged MelanomaThe goal of this clinical research study is to compare how the drug Sprycel (dasatinib) can help to control the tumor in Patients With Acral Lentiginous, Mucosal, or Chronic…NCT01092728·Houston, Texas

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Data from ClinicalTrials.govTerms

Active not recruitingA Clinical Study of Intismeran Autogene (V940) Plus Pembrolizumab in People With High-Risk Melanoma (V940-001)The purpose of this study is to learn if intismeran autogene which is an individualized neoantigen therapy (INT; formerly, called messenger ribonucleic acid \[mRNA\]-4157) with…NCT05933577·Springdale, Arkansas and 164 others

TerminatedAn Open-Label, Randomized, Multicenter Trial of Encorafenib + Binimetinib Evaluating a Standard-dose and a High-dose Regimen in Patients With BRAFV600-mutant Melanoma Brain MetastasisThis is a multicenter, randomized open-label Phase 2 study to assess the safety, efficacy and pharmacokinetic (PK) of 2 dosing regimens of encorafenib + binimetinib combination in…NCT03911869·Los Angeles, California and 24 others

CompletedPhase II Trial of Allovectin-7® for Metastatic MelanomaThe purpose of this clinical trial is to determine if Allovectin-7®, an experimental gene-based immunotherapy, can shrink melanoma tumors.NCT00044356·Tucson, Arizona and 15 others

CompletedInvestigate Safety, Pharmacokinetics and Pharmacodynamics of GSK2118436 & GSK1120212This was an open-label, dose escalation study to investigate the safety, pharmacokinetics, pharmacodynamics and clinical activity of GSK2118436 and GSK1120212 in combination.NCT01072175·Los Angeles, California and 14 others

TerminatedPhase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination With Multiple Standard Chemotherapy or Immunotherapy Agents in Patients With Advanced MalignanciesThis phase Ib trial studies the side effects and best dose of selinexor when given together with several different standard chemotherapy or immunotherapy regimens in treating…NCT02419495·Conroe, Texas and 4 others

RecruitingCryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME TrialThis trial compares cryoablation combined with stereotactic body radiation therapy to stereotactic body radiation therapy alone to see how well they work in treating patients with…NCT04693377·Houston, Texas

TerminatedA Phase 1/2, Open-label, Multi-center Study of the Safety and Efficacy of Alomfilimab (KY1044) as Single Agent and in Combination With Anti-PD-L1 (Atezolizumab) in Adult Patients With Selected Advanced MalignanciesA Phase 1/2, open label, multi-center study to evaluate the safety, efficacy and tolerability of alomfilimab as single agent and in combination with anti-PD-L1 (atezolizumab) in…NCT03829501·Duarte, California and 21 others

CompletedInterferon Alfa and Thalidomide in Treating Patients With Stage IV MelanomaRATIONALE: Interferon alfa may interfere with the growth of cancer cells and slow the growth of the tumor.NCT00026520·Mobile, Alabama and 93 others

TerminatedDoxycycline, Temozolomide and Ipilimumab in MelanomaThe goal of this clinical research study is to find the highest tolerable dose of doxycycline that can be combined with temozolomide and ipilimumab in patients with advanced…NCT01590082·Houston, Texas

CompletedSystemic Therapy With Interferon, Interleukin-2 and BRAF InhibitorThe goal of the Phase I part of this clinical research study is to find the highest tolerable dose of vemurafenib and Aldesleukin (interleukin-2) that can be given in combination…NCT01603212·Houston, Texas

CompletedX4P-001 and Pembrolizumab in Patients With Advanced MelanomaThe goals of this protocol are 1) to investigate the safety and tolerability of X4P-001 in combination with Keytruda® (pembrolizumab) in patients with advanced melanoma, and 2) to…NCT02823405·Atlanta, Georgia and 3 others

Active not recruitingA Phase I Clinical Study to Evaluate the PK Profile, Efficacy, Safety and Immunogenicity of HLX17 vs. Keytruda® in Multiple Resected Solid TumorsThis is a multicenter, randomized, double-blind, parallel-controlled phase I clinical study to evaluate the similarity in PK profile, efficacy, safety, and immunogenicity of HLX17…NCT07160335·Glendale, California and 68 others

TerminatedIPI Biochemotherapy for Chemonaive Patients With Metastatic MelanomaThe goal of the Phase I part of this clinical research study is to find the highest tolerable dose of the drug Yervoy (ipilimumab) that can be given with the drugs Temodar…NCT01409174·Houston, Texas

CompletedA Study to Test the Benefit of a New Anti-cancer Treatment in Patients With Unresectable Advanced MelanomaThe objective of this study is to evaluate the clinical activity of the GSK2132231A immunotherapeutic in patients with MAGE-A3 positive unresectable metastatic melanoma presenting…NCT00942162·Los Angeles, California and 62 others

CompletedA Dose Escalation and Expansion Study of Lomvastomig, a PD-1/TIM-3 Bispecific Antibody, in Participants With Advanced and/or Metastatic Solid TumorsThis is a first-in-human, open-label, multicenter, Phase I multiple-ascending dose (MAD) study of single agent lomvastomig (RO7121661), an anti PD-1 (programmed death-1) and TIM-3…NCT03708328·New York, New York and 16 others

TerminatedA Study of Toca 511, a Retroviral Replicating Vector, Combined With Toca FC in Patients With Solid Tumors or Lymphoma (Toca 6)The purpose of this trial is to evaluate changes in immune activity relative to baseline following treatment with Toca 511 and Toca FC in patients with solid tumors (including…NCT02576665·Denver, Colorado and 2 others

CompletedMAGE-A10ᶜ⁷⁹⁶T for Urothelial Cancer, Melanoma or Head and Neck CancersThis Phase 1 study is designed as a cell dose escalation trial in HLA-A\*02:01 and HLA-A\*02:06 subjects with MAGE-A10 positive urothelial, melanoma or head and neck tumors.NCT02989064·Boston, Massachusetts and 10 others

CompletedCabozantinib S-Malate in Treating Younger Patients With Recurrent or Refractory Solid TumorsThis phase I trial studies the side effects and best dose of cabozantinib S-malate in treating younger patients with solid tumors that have come back or no longer respond to…NCT01709435·Birmingham, Alabama and 22 others

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