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Clareo Health | Melanoma Clinical Trials in Houston | 429 Studies

Clinical Trials MelanomaHouston

Melanoma Clinical Trials in Houston

Find 429 clinical trials for melanoma near Houston, Texas. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Houston

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 61-80 of 429 trials

CompletedA Study Of PF-05082566 As A Single Agent And In Combination With RituximabA study of PF-05082566, a 4-1BB agonist monoclonal antibody (mAb), in patients with solid tumors or b-cell lymphomas, and in combination with rituximab in patients with CD20…NCT01307267·Duarte, California and 41 others

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Data from ClinicalTrials.govTerms

CompletedNeoadjuvant and Adjuvant Checkpoint BlockadeThis randomized phase II trial studies how well nivolumab with or without ipilimumab or relatlimab before surgery works in treating patients with stage IIIB-IV melanoma that can…NCT02519322·New York, New York and 1 other

CompletedA Trial of ABI-007 Versus Dacarbazine in Previously Untreated Patients With Metastatic Malignant MelanomaThe main purpose of this research study is to compare the safety, tolerability, and anti tumor activity of an investigational drug, ABI-007 versus Dacarbazine in patients with…NCT00864253·Birmingham, Alabama and 111 others

CompletedA Study of SEA-CD40 Given With Other Drugs in CancersThis trial is being done to see if an experimental drug (SEA-CD40) works when it's given with other cancer drugs to treat some types of cancer.NCT04993677·Springdale, Arkansas and 28 others

CompletedPilot Study of Nivolumab w/Ipilimumab or Relatlimab in Surgically Resectable Melanoma Brain MetastasesThe purpose of this pilot study is to determine the safety and feasibility of giving a single dose of Nivolumab with Ipilimumab or Relatlimab in participants with brain metastases…NCT05704933·Tampa, Florida and 1 other

RecruitingA Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)This study is researching an experimental drug called fianlimab (also known as REGN3767), combined with another medication called cemiplimab (also known as REGN2810), called…NCT06246916·Chandler, Arizona and 112 others

RecruitingA Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal MelanomaThe purpose of this study is to measure the clinical benefits of the combination of RP2 and nivolumab as compared with the combination of nivolumab and ipilimumab in patients with…NCT06581406·Scottsdale, Arizona and 32 others

RecruitingA Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)This is an open-label, multicenter Phase 2 study evaluating BMS-986504 in participants with advanced and/or metastatic solid tumors that have MTAP deletion.NCT07492680·San Francisco, California and 57 others

CompletedSTAT3 Inhibitor WP1066 in Treating Patients With Recurrent Malignant Glioma or Progressive Metastatic Melanoma in the BrainThis phase I trial studies the side effects and best dose of STAT3 inhibitor WP1066 in treating patients with malignant glioma that has come back or melanoma that has spread to…NCT01904123·Houston, Texas

WithdrawnNeoadjuvant Nivolumab+Ipilimumab Followed by Adjuvant Nivolumab or Neoadjuvant Nivolumab+Ipilimumab Followed by Adjuvant Observation Compared With Adjuvant Nivolumab in Treatment-Naive High-risk Melanoma ParticipantsThe purpose of this study is to evaluate the role of neoadjuvant immunotherapy and to demonstrate high pathologic complete response (pCR) and near pCR rates in melanoma…NCT04495010·Gilbert, Arizona and 117 others

CompletedSafety of TKI258 in Advanced/Metastatic Melanoma SubjectsThis study is an open-label, dose-escalating study to delineate the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of TKI258.NCT00303251·Louisville, Kentucky and 2 others

CompletedStudy Of OX40 Agonist PF-04518600 Alone And In Combination With 4-1BB Agonist PF-05082566To assess the safety and tolerability at increasing dose levels of PF-04518600 alone or in combination wtih PF-05082566 in patients with select advanced or metastatic carcinoma in…NCT02315066·Los Angeles, California and 29 others

UnknownTavo and Pembrolizumab in Patients With Stage III/IV Melanoma Progressing on Either Pembrolizumab or Nivolumab TreatmentKeynote 695 is Phase 2 study of intratumoral tavokinogene telseplasmid (tavo; pIL-12) Electroporation (EP) plus IV Pembrolizumab.NCT03132675·Tucson, Arizona and 32 others

CompletedGenetically Modified Therapeutic Autologous Lymphocytes Followed by Aldesleukin in Treating Patients With Stage III or Metastatic MelanomaThis phase I/II trial studies how well genetically modified therapeutic autologous lymphocytes (patient's own white blood cells) followed by aldesleukin work in treating patients…NCT01740557·Houston, Texas

CompletedSafety Study of Enoblituzumab (MGA271) in Combination With Ipilimumab in Refractory CancerThe purpose of this study is to evaluate the safety of enoblituzumab (MGA271) in combination with Yervoy (ipilimumab) when given to patients with B7-H3-expressing melanoma…NCT02381314·Los Angeles, California and 9 others

CompletedA Treatment Combination for Patients With Unresectable Stage III or Stage IV MelanomaThe objectives of this study are to compare the anti-tumor activity as measured by Progression Free Survival (PFS) and tolerability of Sorafenib in combination with Paclitaxel and…NCT00111007·Birmingham, Alabama and 65 others

Active not recruitingAerosolized Aldesleukin in Treating Patients With Lung MetastasesThis phase I/II trial studies the side effects and best dose of aerosolized aldesleukin and to see how well it works in treating patients with cancer that has spread from the…NCT01590069·Houston, Texas

CompletedStudy of HBI-8000 With Nivolumab in Melanoma, Renal Cell Carcinoma and Non-Small Cell Lung CancerA Phase 1b/2 Study to Assess the Safety and Efficacy of HBI-8000 in Combination with Nivolumab in Patients with Advanced Solid Tumors Including Melanoma, Renal Cell Carcinoma…NCT02718066·Phoenix, Arizona and 5 others

RecruitingA Study of IBI363 in Subjects with Advanced Solid MalignanciesThis is a Phase 2, open-label, multicenter study designed to evaluate the efficacy, safety and tolerability of IBI363 (study drug) in subjects with advanced, refractory solid…NCT06281678·San Francisco, California and 8 others

RecruitingA Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid TumorsThe purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary efficacy of KIN-2787 in adults with BRAF/NRAS-mutated advanced or…NCT04913285·Los Angeles, California and 47 others

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