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Clareo Health | Lupus Clinical Trials in Philadelphia | 54 Studies

Clinical Trials LupusPhiladelphia

Lupus Clinical Trials in Philadelphia

Find 54 clinical trials for lupus near Philadelphia, Pennsylvania. Connect with research centers in your area.

All Lupus trials nationwide All trials in Philadelphia

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

Who can join

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Showing 41-54 of 54 trials

Active not recruitingA Study of CC-97540 (BMS-986353 or Zola-cel), CD19-Targeted NEX-T CAR T Cells, in Participants With Active SLE Despite Immunosuppressants (Breakfree-SLE)The purpose of this study is to evaluate the efficacy, safety and drug levels of CC-97540 in participants with active systemic lupus erythematosus (SLE) including lupus nephritis…NCT07015983·Phoenix, Arizona and 96 others

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Data from ClinicalTrials.govTerms

CompletedDouble-Blinded, Randomized, Placebo-Controlled Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Biochemical Activity of Intravenous Cpn10 Administration in Subjects With Mild to Moderate SLE.The primary objective of the study is to evaluate the safety, tolerability, and efficacy of 4 weeks intravenous treatment with Cpn10 in subjects with mild to moderate active SLE.NCT01838694·Miami, Florida and 5 others

RecruitingCD19-Directed Chimeric Antigen Receptor Autologous T Cells (CART19) for LupusThis is a single-center, single-arm, open-label phase 1/2 study of CART19 in children and young adults with refractory Systemic lupus erythematosus (SLE), including both patients…NCT06839976·Philadelphia, Pennsylvania

Not yet recruitingA Study of BMS-986553 in Participants With Refractory Autoimmune DiseasesThe purpose of this study is to evaluate the safety and tolerability of BMS-986553, CD19 in vivo Chimeric Antigen Receptor (CAR) T cells, in participants with refractory…NCT07873931·Newport Beach, California and 22 others

CompletedA Study to Evaluate the Safety of Rituximab Retreatment in Subjects With Systemic Lupus ErythematosusThis is a Phase II/III, randomized, double-blind, placebo-controlled, multicenter study to evaluate the efficacy and safety of rituximab compared with placebo when combined with a…NCT00137969·Birmingham, Alabama and 64 others

CompletedEfficacy and Safety of Two Doses of Anifrolumab Compared to Placebo in Adult Subjects With Active Systemic Lupus ErythematosusThe purpose of this study is to evaluate the efficacy and safety of an intravenous treatment regimen of two doses of anifrolumab versus placebo in adult subjects with moderately…NCT02446912·Birmingham, Alabama and 144 others

CompletedA Crossover Study to Compare RAYOS to IR Prednisone to Improve Fatigue and Morning Symptoms for SLETo compare the effect of RAYOS® versus immediate-release (IR) prednisone on fatigue as measured by Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F).NCT03098823·Los Angeles, California and 20 others

CompletedA Study of LY2127399 in Participants With Systemic Lupus ErythematosusThe purpose of this SLE study is to evaluate the efficacy, safety and tolerability of two different doses of LY2127399 administered in participants with active SLE.NCT01196091·Birmingham, Alabama and 191 others

RecruitingAutologous Stem Cell Transplant (ASCT) for Autoimmune DiseasesA subset of autoimmune diseases (ADs) in children and young adults are life-threatening and unresponsive to conventional treatments.NCT05029336·Philadelphia, Pennsylvania

Active not recruitingPhase 2 Placebo-Controlled Study to Assess the Safety and Efficacy of ESK-001 in Active Systemic Lupus ErythematosusThe purpose of this study is to assess the clinical efficacy, safety, PK, and PD of multiple dose levels of ESK-001 compared with placebo in adult patients with SLE.NCT05966480·Anniston, Alabama and 168 others

CompletedSafety of Estrogens in Lupus: Birth Control PillsSafety of Estrogens in Lupus Erythematosus - National Assessment (SELENA) is a study to test whether women with systemic lupus erythematosus (SLE or lupus) can safely use estrogen.NCT00000420·Los Angeles, California and 14 others

CompletedSpine Quantitative Computed Tomography (QCT) for the Assessment of Osteoporosis on ChildrenThe purpose of this study is to compare healthy children to children who have systemic lupus erythematosus (SLE).NCT01330368·Philadelphia, Pennsylvania

CompletedStudy to Evaluate BIIB059 (Litifilimab) in Cutaneous Lupus Erythematosus (CLE) With or Without Systemic Lupus Erythematosus (SLE)The primary purpose of the study is to evaluate the efficacy of BIIB059 (litifilimab) in reducing disease activity in participants with systemic lupus erythematosus (SLE) with…NCT02847598·Anniston, Alabama and 127 others

TerminatedA Study of Ustekinumab in Participants With Active Systemic Lupus ErythematosusThe purpose of this study is to evaluate the efficacy of ustekinumab in participants with active systemic lupus erythematosus (SLE) who have not adequately responded to one or…NCT03517722·Anniston, Alabama and 203 others

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