Lung Cancer Clinical Trials

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An Observational Study on Predicting the Efficacy of Immunotherapy for NSCLC Based on LIRAscore

NCT06232265

This is a multi-center, observational clinical study to explore the role of LIRAscore in predicting immunotherapy monotherapy and combination with chemotherapy efficacy and prognosis in locally advanced or metastatic non-small-cell lung cancer. The study plans to enroll 108 patients. The primary endpoint of this study was ORR, and secondary endpoints were PFS, OS, DoR, DCR, and safety.

Non-small Cell Lung Cancer

Nanfang Hospital, Southern Medical University108 participantsStarted Sep 2023

Guangzhou, Guangdong, China

RECRUITINGPhase 3

Phase III Study of TY-9591 in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer (FLETEO)

NCT05382728

To assess the efficacy and safety of TY-9591 versus Osimertinib in patients with locally advanced or Metastatic Non Small Cell Lung Cancer.

NSCLCEGFR Activating Mutation

TYK Medicines, Inc680 participantsStarted Jun 2022

Changsha, Hunan, China • Shanghai, Shanghai Municipality, China

An Observational Study on Predicting the Efficacy of Immunotherapy for NSCLC Based on LIRAscore

Phase III Study of TY-9591 in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer (FLETEO)

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