Lung Cancer Clinical Trials

Showing 921-940 of 3,692 trials

To Evaluate Efficacy and Safety of TT-00420 (Tinengotinib) as Monotherapy and Combination Therapy in Patients With Advanced Solid Tumors

NCT05253053

This is a Phase Ib/II, multicenter, open-label study to evaluate the safety and preliminary efficacy of TT-00420 tablet, as monotherapy or in combination regimens, in patients with advanced solid tumors (solid tumor, BTC and TNBC).

Advanced Solid TumorCholangiocarcinomaBiliary Tract Cancer+8 more

TransThera Sciences (Nanjing), Inc.84 participantsStarted Apr 2022

Wuhu, Anhui, China • Zhengzhou, Henan, China • Changsha, Hunan, China +6 more locations

TERMINATEDPhase 1/2

AVID100 in Advanced Epithelial Carcinomas

NCT03094169

Approximately 90 male and female patients with documented solid tumor malignancies of epithelial origin that are locally advanced or metastatic, and either refractory to standard therapy or for whom no standard therapy is available, will be entered into this Phase 1a/2a, multicenter, open-label, dose-escalation, cohort study of AVID100. Phase 2a will include evaluation of patient with EGFR-overexpressing squamous histology non-small cell lung cancer, squamous cell carcinoma of the head and neck, and triple negative breast cancer

Solid Tumor, AdultTriple Negative Breast CancerHead and Neck Squamous Cell Carcinoma+1 more

Formation Biologics49 participantsStarted Feb 2017

New Haven, Connecticut, United States • Grand Rapids, Michigan, United States • New York, New York, United States +7 more locations

To Evaluate Efficacy and Safety of TT-00420 (Tinengotinib) as Monotherapy and Combination Therapy in Patients With Advanced Solid Tumors

AVID100 in Advanced Epithelial Carcinomas

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