Liver Disease Clinical Trials

Showing 401-420 of 1,279 trials

HELIO Liver Test Performance Study in China (HEPATIC)

NCT05053412

De-identified whole blood and serum samples are collected for the purpose of evaluating the performance (sensitivity/specificity) of the HelioLiver Test for the detection of hepatocellular carcinoma (HCC).

Hepatocellular Carcinoma and Liver Disease

Helio Genomics1,556 participantsStarted Sep 2021

Beijing, Beijing Municipality, China • Beijing, China

COMPLETEDPhase 1/2

Normothermic Liver Preservation Trial

NCT03089840

This trial is to assess the safety and efficacy of normothermic machine perfusion (NMP) as an organ preservation method prior to transplantation using the OrganOx metra™ device.

End Stage Liver DiseaseLiver Diseases

University of Alberta106 participantsStarted Feb 2017

Edmonton, Alberta, Canada

Enrolling By InvitationNA

Reducing Non-Alcoholic Steatohepatitis

NCT06519448

The goal of this clinical trial is to learn if empagliflozin works to treat non-alcoholic steatohepatitis in adults. The objectives are: Primary Objective To evaluate the change in histological grading and staging of NASH in patients with confirmed non-alcoholic steatohepatitis (NASH) treated with empagliflozin for a duration of 48 weeks. Secondary Objective To evaluate the change in findings from non-invasive liver elasticity measurements, laboratory tests, and anthropometric assessments after 48 weeks of empagliflozin administration. Participants will: Take empagliflozin every day for 12 months. Visit the clinic according to a protocol at weeks: 1, 2, 4, 12, 24, 36, 48 Visits includes checkups and tests (blood count, basic biochemistry, glycosylated hemoglobin, anthropometry, non-invasive liver stiffness measurement).

Non-alcoholic SteatohepatitisLiver DiseasesDiabetes Mellitus, Type 2+1 more

Military University Hospital, Prague30 participantsStarted Apr 2024

Prague, Czechia

HELIO Liver Test Performance Study in China (HEPATIC)

Normothermic Liver Preservation Trial

Reducing Non-Alcoholic Steatohepatitis

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Effect of High Intensity Exercise Rehabilitation on Liver Function and Insulin Sensitivity in Patients With MASLD