Leukemia Clinical Trials in Philadelphia

Showing 1121-1140 of 1,502 trials

BAY1436032 in Patients With Mutant IDH1(mIDH1) Advanced Acute Myeloid Leukemia (AML)

NCT03127735

To determine the maximum tolerated and / or recommended Phase II dose of oral mutant IDH1 (mIDH1) inhibitor BAY1436032 and to characterize its safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary clinical efficacy in patients with mIDH1-R132X advanced acute myeloid leukemia (AML)

Leukemia, Myeloid, Acute

Bayer27 participantsStarted Jun 2017

Buffalo, New York, United States • New York, New York, United States • The Bronx, New York, United States +10 more locations

COMPLETEDPhase 3< 1 mile

LUX-Lung 8: A Phase III Trial of Afatinib (BIBW 2992) Versus Erlotinib for the Treatment of Squamous Cell Lung Cancer After at Least One Prior Platinum Based Chemotherapy

NCT01523587

This randomised, open-label phase III trial will be performed in patients with advanced squamous cell carcinoma of the lung requiring second-line treatment after receiving first-line platinum-based chemotherapy. The primary objective of this trial is to compare the efficacy of BIBW 2992 to erlotinib as second-line treatment in this group of patients.

Carcinoma, Non-Small-Cell Lung

Boehringer Ingelheim795 participantsStarted Mar 2012

Chandler, Arizona, United States • La Jolla, California, United States • Sacramento, California, United States +189 more locations

BAY1436032 in Patients With Mutant IDH1(mIDH1) Advanced Acute Myeloid Leukemia (AML)

LUX-Lung 8: A Phase III Trial of Afatinib (BIBW 2992) Versus Erlotinib for the Treatment of Squamous Cell Lung Cancer After at Least One Prior Platinum Based Chemotherapy

Leukemia Trials in Other Cities

Safety and Efficacy of the ELAD System (ELAD) to Treat Acute Liver Failure (ALF)

Quality of Life and Care Needs of Patients With Persistent or Recurrent Ovarian Cancer, Fallopian Tube Cancer, or Peritoneal Cancer

A Study Comparing the Combination of Trabectedin (YONDELIS) and DOXIL/CAELYX With DOXIL/CAELYX for the Treatment of Advanced-Relapsed Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

A Randomized, Double-Blind, Placebo-Controlled Study of Idelalisib in Combination With Rituximab for Previously Treated Chronic Lymphocytic Leukemia (CLL)

Safety and Dose Ranging Study of Samalizumab to Treat Relapsing or Refractory CLL or MM

Study of Orally Administered AG-881 in Patients With Advanced Hematologic Malignancies With an IDH1 and/or IDH2 Mutation

A Phase I, Multicenter Dose Escalation Study in Patients With Hairy Cell Leukemia

Persistent Pulmonary Hypertension of the Newborn (PPHN) Observational Study

Antenatal Phenobarbital to Prevent Neonatal Intracranial Hemorrhage

Exosurf Neonatal and Survanta for Treatment of Respiratory Distress Syndrome

Efficacy and Safety of Momelotinib Combined With Trametinib in Adults With Metastatic KRAS-mutated Non-Small Cell Lung Cancer (NSCLC) Who Have Failed Platinum-Based Chemotherapy Preceded by a Dose-finding Lead-in Phase

Early Diagnosis of Candidiasis in Premature Infants

Observational Study of Surgical Treatment of Necrotizing Enterocolotis

Open-label Study of Nelotanserin in Lewy Body Dementia With Visual Hallucinations or REM Sleep Behavior Disorder

A Study for Patients With Acute Leukemia

LDK378 in Crizotinib naïve Adult Patients With ALK-activated Non-small Cell Lung Cancer

Frequency of Screening and SBT Technique Trial

Phase IV EORTC Quality of Life Module for Patients With Chronic Myeloid Leukemia

Other Conditions in Philadelphia