Leukemia Clinical Trials in Baltimore

Showing 1201-1220 of 1,652 trials

Azacitidine and Entinostat in Treating Patients With Stage I Non-Small Cell Lung Cancer That Has Been Removed By Surgery

NCT01207726

This study combines the deoxyribonucleic acid (DNA) methyltransferase inhibitor, 5-azacitidine (5-AZA), with an orally bioavailable histone deacetylase inhibitor, entinostat (SNDX-275), for the adjuvant treatment of patients with resected stage I non-small cell lung cancer (NCSLC).

Stage IA Non-Small Cell Lung CarcinomaStage IB Non-Small Cell Lung Carcinoma

National Cancer Institute (NCI)13 participantsStarted Sep 2010

Los Angeles, California, United States • Tampa, Florida, United States • Annapolis, Maryland, United States +6 more locations

COMPLETEDPhase 1< 1 mile

Red Cell Transfusion Goals in Patients With Acute Leukemias

NCT02086773

The purpose of this study to determine if a lower hemoglobin transfusion threshold, 7 g/dL, has a safety profile similar to that of the current standard transfusion threshold of 8 g/dL.

Acute Lymphoblastic LeukemiaAcute Lymphocytic Leukemia (ALL)Acute Myelogenous Leukemia (AML)+1 more

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins90 participantsStarted Apr 2014

Baltimore, Maryland, United States

COMPLETEDPhase 1< 1 mile

Azacitidine Plus Phenylbutyrate in Treating Patients With Advanced or Metastatic Solid Tumors That Have Not Responded to Previous Treatment

NCT00005639

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: This phase I trial is studying the side effects and best dose of azacitidine plus phenylbutyrate in treating patients with advanced or metastatic solid tumors that have not responded to previous treatment.

LymphomaSmall Intestine CancerUnspecified Adult Solid Tumor, Protocol Specific

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins34 participantsStarted Mar 2000

Baltimore, Maryland, United States

Azacitidine and Entinostat in Treating Patients With Stage I Non-Small Cell Lung Cancer That Has Been Removed By Surgery

Red Cell Transfusion Goals in Patients With Acute Leukemias

Azacitidine Plus Phenylbutyrate in Treating Patients With Advanced or Metastatic Solid Tumors That Have Not Responded to Previous Treatment

Leukemia Trials in Other Cities

Temsirolimus and Bevacizumab in Treating Patients With Advanced Endometrial, Ovarian, Liver, Carcinoid, or Islet Cell Cancer

Antenatal Phenobarbital to Prevent Neonatal Intracranial Hemorrhage

Persistent Pulmonary Hypertension of the Newborn (PPHN) Observational Study

Exosurf Neonatal and Survanta for Treatment of Respiratory Distress Syndrome

Safety and Efficacy of the ELAD System (ELAD) to Treat Acute Liver Failure (ALF)

Efficacy and Safety of Momelotinib Combined With Trametinib in Adults With Metastatic KRAS-mutated Non-Small Cell Lung Cancer (NSCLC) Who Have Failed Platinum-Based Chemotherapy Preceded by a Dose-finding Lead-in Phase

Quality of Life and Care Needs of Patients With Persistent or Recurrent Ovarian Cancer, Fallopian Tube Cancer, or Peritoneal Cancer

LUX-Lung 8: A Phase III Trial of Afatinib (BIBW 2992) Versus Erlotinib for the Treatment of Squamous Cell Lung Cancer After at Least One Prior Platinum Based Chemotherapy

Safety and Dose Ranging Study of Samalizumab to Treat Relapsing or Refractory CLL or MM

Study of Orally Administered AG-881 in Patients With Advanced Hematologic Malignancies With an IDH1 and/or IDH2 Mutation

GRN1005 in Non-Small Cell Lung Cancer (NSCLC) Patients With Brain Metastases (GRABM-L)

Observational Study of Surgical Treatment of Necrotizing Enterocolotis

Early Diagnosis of Candidiasis in Premature Infants

Volasertib + Decitabine in Patients With Acute Myeloid Leukemia (AML)

Open-label Study of Nelotanserin in Lewy Body Dementia With Visual Hallucinations or REM Sleep Behavior Disorder

LDK378 in Crizotinib naïve Adult Patients With ALK-activated Non-small Cell Lung Cancer

Phase IV EORTC Quality of Life Module for Patients With Chronic Myeloid Leukemia

Other Conditions in Baltimore