Leukemia Clinical Trials in Austin

Showing 681-700 of 1,100 trials

Study of PTC299 (Emvododstat) in Relapsed/Refractory Acute Leukemias

NCT03761069

This is an open-label, non-randomized, Phase 1b study to evaluate the safety, pharmacokinetics (PK) profiles, and preliminary evidence of antitumor activity of PTC299 and the metabolite, O-desmethyl PTC299, in participants with relapsed/refractory acute myeloid leukemia (AML) who have exhausted standard available therapies known to provide clinical benefit. The study is designed as a series of cohort-based dose escalations. For each cohort, a minimum of 3 evaluable participants with PK and safety data will be assessed. Additional participants will be recruited if additional PK data are needed to assess mean exposure based on the observed variability.

Leukemia, Myeloid, AcuteAML

PTC Therapeutics33 participantsStarted Oct 2018

Aurora, Colorado, United States • New Haven, Connecticut, United States • Detroit, Michigan, United States +14 more locations

TERMINATEDPhase 2< 1 mile

Efficacy Study of Oral Seliciclib to Treat Non-Small Cell Lung Cancer

NCT00372073

A phase 2 study to evaluate efficacy of oral seliciclib in treating non-small cell lung cancer (NSCLC).

Non-small Cell Lung Cancer

Cyclacel Pharmaceuticals, Inc.187 participantsStarted Aug 2006

Tucson, Arizona, United States • Fountain Valley, California, United States • New Port Richey, Florida, United States +17 more locations

Study of PTC299 (Emvododstat) in Relapsed/Refractory Acute Leukemias

Efficacy Study of Oral Seliciclib to Treat Non-Small Cell Lung Cancer

Leukemia Trials in Other Cities

Study in Adult and Adolescent Subjects With Seasonal Allergic Rhinitis (SAR)

Comprehensive Patient Questionnaires in Predicting Complications in Older Patients With Gynecologic Cancer Undergoing Surgery

AR101 Real-World Open-Label Extension Study

Combination Chemotherapy in Treating Young Patients With Down Syndrome and Acute Myeloid Leukemia or Myelodysplastic Syndromes

Long Term Safety and Efficacy Trial of Beclomethasone Dipropionate - Hydrofluoroalkane (BDP-HFA) 320 mcg in Allergic Rhinitis

Double Cord Versus Haploidentical (BMT CTN 1101)

DOSE Trial of Opioid Sparing Effect

Study of AMV564 in Subjects With Advanced Solid Tumors

Enoblituzumab (MGA271) in Children With B7-H3-expressing Solid Tumors

A Study of Venetoclax in Combination With Cobimetinib and Venetoclax in Combination With Idasanutlin in Patients With Relapsed or Refractory Acute Myeloid Leukemia Who Are Not Eligible for Cytotoxic Therapy

Homoharringtonine (Omacetaxine Mepesuccinate) in Treating Patients With Chronic Myeloid Leukemia (CML) With the T315I BCR-ABL Gene Mutation

Safety of and Immune Response to a Novel Human Papillomavirus Vaccine in HIV Infected Children

Safety of and Immune Response to the Human Papillomavirus (HPV) Vaccine in HIV-Infected Women

A Study of Venetoclax and AMG 176 in Patients With Relapsed/Refractory Hematologic Malignancies

Pemetrexed and/or Sunitinib as Second-Line Therapy in Treating Patients With Stage IIIB or Stage IV Non-small Cell Lung Cancer

Safety Study of MGA271 in Refractory Cancer

A Phase 1 Study of Nivolumab (BMS-936558) in Subjects With Advanced or Recurrent Malignancies

A Study of MM-121 in Combination With Chemotherapy Versus Chemotherapy Alone in Heregulin Positive NSCLC

Other Conditions in Austin