Kidney Disease Clinical Trials

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A Phase 1 Dose Escalation Study to Evaluate Safety and Pharmacokinetics (PK) of VX-840 in Healthy Participants

NCT05324410

The purpose of this study is to evaluate the safety, tolerability, and PK of single and multiple ascending doses of VX-840 in healthy participants.

APOL1-mediated Kidney Disease

Vertex Pharmaceuticals Incorporated88 participantsStarted Apr 2022

Lenexa, Kansas, United States

COMPLETEDNA

Dialysis Training Therapy: The DiaTT Trial

NCT03885102

DiaTT is an interventional, cluster-randomized (1:1), multicenter trial for patients with chronic kidney disease undergoing hemodialysis (n=1,100). This trial will test the effectiveness (by change of sit-to-stand test between baseline and 12 months) of intradialytic exercise training (ET) and health literacy counseling (HLC) for 12 months (Intervention group) in comparison to control group (usual care, UC; no ET, no HLC).

Chronic Kidney DiseasesHemodialysis

Prof. Dr. med. Martin Halle1,211 participantsStarted Apr 2019

Amberg, Bavaria, Germany • Aschaffenburg, Bavaria, Germany • Bamberg, Bavaria, Germany +18 more locations

A Phase 1 Dose Escalation Study to Evaluate Safety and Pharmacokinetics (PK) of VX-840 in Healthy Participants

Dialysis Training Therapy: The DiaTT Trial

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