Kidney Disease Clinical Trials

Showing 1241-1260 of 3,346 trials

Prospective Observational Analysis Of CR With Sunitinib Treatment In mRCC Patients

NCT01934452

This prospective study will investigate the characteristics of mRCC patients at time of CR in comparison with mRCC patients non on CR treated with Sunitinib, in order to provide some answers/ refection leads to the following questions : Can we identify blood specificity at time of CR vs non on CR? Shall we distinguish CR with sunitinib alone from combined CR (sunitinib with local treatment), while in clinical report these 2 cohorts present similar time to recurrence (ALBIGES, ASCO 2010)? Can we identify potential predictive serum biomarkers of recurrence? (With the aim of isolating blood biomarker that can help on treatment discontinuation decision?)

Complete Remission in Renal Cell Carcinoma

Pfizer77 participantsStarted May 2015

Marseille, Cedex 5, France • Strasbourg, Cedex, France • Angers, France +11 more locations

UNKNOWNPhase 2

Pucotenlimab Combined With Lenvatinib as a Neodjuvant Therapy for Non Clear Cell Renal Cell Carcinoma

NCT06129955

Through the neoadjuvant treatment with a combination of Pucotenlimab and Lenvatinib, it eventually enables the successful and safe implementation of partial nephrectomy in patients with localized renal cancer, who have indications for nephron-sparing surgery but face significant difficulty in kidney preservation (T1b with an endophytic component ≥75% or T2).

Renal Cell Carcinoma

Sun Yat-sen University47 participantsStarted Nov 2023

Guangzhou, Other (Non U.s.), China

Prospective Observational Analysis Of CR With Sunitinib Treatment In mRCC Patients

Pucotenlimab Combined With Lenvatinib as a Neodjuvant Therapy for Non Clear Cell Renal Cell Carcinoma

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