Kidney Disease Clinical Trials

Showing 3461-3480 of 3,902 trials

SOCRATES: Steroid or Cyclosporine Removal After Transplantation Using Everolimus

NCT00371826

The aim of this study is to assess the safety and efficacy of corticosteroid discontinuation versus cyclosporine micro emulsion discontinuation in recipients receiving reduced exposure cyclosporine micro emulsion and corticosteroids plus enteric-coated mycophenolate sodium (EC-MPS) initially, changed to everolimus at 2 weeks post-transplant. These two groups will be compared to a third control group, who will receive treatment consisting of cyclosporine micro emulsion, enteric-coated mycophenolate sodium (EC-MPS) and steroids.

Renal Transplanted Recipients

Novartis Pharmaceuticals126 participantsStarted Mar 2006

NSW, Australia • NSW, Australia • QLD, Australia +4 more locations

COMPLETED

Analysis of Remote-ischemic Preconditioning Effects on Kidney Function

NCT01925235

Patients with impaired renal function are at elevated risk for development of acute kidney injury (AKI). AKI is associated with increased risk for cardiovascular morbidity and mortality. Effective AKI prevention strategies are needed. Remote ischemic preconditioning (RIPC) is a novel and successful strategy to attenuate contrast medium induced AKI in patients undergoing elective coronary angiography. The retrospective RenPro-TAVI Trial was designed to test the hypothesis whether remote ischemic preconditioning might attenuate kidney injury in patients receiving transcatheter aortic valve implantation (TAVI). Patients with impaired renal function undergoing TAVI will be evaluated in respect whether they received remote ischemic preconditioning before the procedure or not. This study will give insight if RIPC might be beneficial in these patients.

Renal FunctionRenal Injury

University of Cologne18 participantsStarted Mar 2010

Cologne, North Rhine-Westphalia, Germany

SOCRATES: Steroid or Cyclosporine Removal After Transplantation Using Everolimus

Analysis of Remote-ischemic Preconditioning Effects on Kidney Function

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