Kidney Disease Clinical Trials in Chicago

Showing 121-140 of 407 trials

Effects of Itraconazole and Rifampin on the Blood Tazemetostat Levels

NCT04537715

The participants of this study will have advanced malignancies (also known as advanced cancer). The main aim of this trial will be to study the blood levels (known as pharmacokinetics) of the tazemtostat (the study drug) when administered in combination with another drug. Part 1 of the study will evaluate the interaction between the drugs tazemetostat and itraconazole. Part 2 of the study will evaluate the interaction between the drugs tazemetostat and rifampin For both Parts 1 and 2, safety and the level that effects of the study drug can be tolerated (known as tolerability) will be assessed throughout.

All MalignanciesAdvanced MalignanciesHematologic Malignancy+9 more

Epizyme, Inc.42 participantsStarted Apr 2020

Encinitas, California, United States • Los Angeles, California, United States • Chicago, Illinois, United States +7 more locations

COMPLETEDPhase 22.2 miles

Testing Cabozantinib, Crizotinib, Savolitinib and Sunitinib in Kidney Cancer Which Has Progressed

NCT02761057

This phase II trial studies how well cabozantinib s-malate, crizotinib, savolitinib, or sunitinib malate work in treating patients with kidney cancer that has spread from where it started to nearby tissue or lymph nodes or to other places in the body. Cabozantinib s-malate, crizotinib, savolitinib, and sunitinib malate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. It is not yet known whether giving cabozantinib s-malate, crizotinib, or savolitinib will work better in treating patients with kidney cancer compared to sunitinib malate.

Locally Advanced Papillary Renal Cell CarcinomaMetastatic Papillary Renal Cell CarcinomaStage III Renal Cell Cancer AJCC v7+4 more

National Cancer Institute (NCI)152 participantsStarted Jul 2016

Anchorage, Alaska, United States • Anchorage, Alaska, United States • Anchorage, Alaska, United States +592 more locations

Effects of Itraconazole and Rifampin on the Blood Tazemetostat Levels

Testing Cabozantinib, Crizotinib, Savolitinib and Sunitinib in Kidney Cancer Which Has Progressed

Kidney Disease Trials in Other Cities

Interactive Computer-adaptive Chronic Kidney Disease Education Program

Comparison of Chronocort Versus Standard Hydrocortisone Replacement Therapy in Participants Aged 16 Years and Over With Congenital Adrenal Hyperplasia

A Study of AGS-16C3F vs. Axitinib in Metastatic Renal Cell Carcinoma

Eliminating the Need for Pancreas Biopsy Using Peripheral Blood Cell-free DNA

Study to Evaluate the Safety and Efficacy of SPR001 in Subjects With Classic Congenital Adrenal Hyperplasia

Chimney EndoVascular Aneurysm Sealing Of New Expanded Indication

A Study of Pazopanib With or Without Abexinostat in Patients With Locally Advanced or Metastatic Renal Cell Carcinoma (RENAVIV)

Interventional Study of INCB 99280 With Ipilimumab in Participants With Select Solid Tumors

A Trial of Belzutifan (PT2977, MK-6482) in Combination With Cabozantinib in Patients With Clear Cell Renal Cell Carcinoma (ccRCC) (MK-6482-003)

A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08)

Trial to Assess Safety and Efficacy of Lenvatinib (18 mg vs. 14 mg) in Combination With Everolimus in Participants With Renal Cell Carcinoma

Urine CXCL10 Monitoring Trial in Kidney Transplant

Aldosterone bloCkade for Health Improvement EValuation in End-stage Renal Disease

Open Label Pharmacokinetic Study of SAR302503 in Subjects With Renal Impairment

SL-279252 (PD1-Fc-OX40L) in Subjects With Advanced Solid Tumors or Lymphomas

A Study of Autologous Renal Autologous Cell Therapy (REACT) in Patients With Diabetic Chronic Kidney Disease

Study of Nanrilkefusp Alfa Alone and With Pembrolizumab in Adult Patients With Advanced/Metastatic Solid Tumors

Communication During Hospitalization About Resuscitation Trial

Other Conditions in Chicago