Heart Disease Clinical Trials

Showing 5081-5100 of 7,313 trials

Randomized, Open Label Trial of 6 Months Versus 12 Months DAPT After Drug-Eluting Stent in STEMI

NCT01459627

OBJECTIVE OF THE STUDY: To test the hypothesis that 6 months DAPT (Dual anti-platelet therapy) after second generation DES (Drug Eluting Stent) implantation in STEMI (ST elevation Myocardial Infarction) is not inferior to 12 months DAPT in terms of clinical outcomes (composite endpoint of all-cause mortality, any MI, any revascularization, stroke and major bleeding at 18 months after randomization). The trial will incorporate two registers studying respectively the safety outcomes of Bivalirudin and Prasugrel combination and Bivalirudin and Ticagrelor combination at 2 and 30 days. Finally the trial design permits assessment of the clinical outcomes after primary PCI for treatment of STEMI with the new Resolute Integrity (Medtronic Santa Rosa Ca, USA) stent at 30 days and 6 months.

Myocardial InfarctionCardiovascular Disease

Maasstad Hospital1,100 participantsStarted Dec 2011

Amsterdam, Netherlands • Breda, Netherlands • Enschede, Netherlands +13 more locations

UNKNOWNNA

Efficacy of External CounterPulsation for Postoperative Coronary Artery Bypass Grafting Patients

NCT03235323

The aim of this study is to evaluate the effect of External CounterPulsation on postoperative heart function and vein graft failure rates of coronary artery bypass grafting patients.

CounterpulsationCoronary Artery Bypass

Mengya Liang120 participantsStarted Sep 2017

Guangzhou, Guangdong, China

Randomized, Open Label Trial of 6 Months Versus 12 Months DAPT After Drug-Eluting Stent in STEMI

Efficacy of External CounterPulsation for Postoperative Coronary Artery Bypass Grafting Patients

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