Heart Disease Clinical Trials

Showing 3401-3420 of 7,313 trials

Prevalence, Incidence and Characteristics of NAFLD/NASH in Type 1 Diabetes Mellitus

NCT04664036

Nonalcoholic fatty liver disease (NAFLD) is a condition characterized by intrahepatic fat accumulation. It is closely related to insulin resistance. To date, it remains unclear whether NAFLD is common in patients with type 1 diabetes or if NAFLD translates into an increased health burden in this population. Screening for NAFLD is challenging due to the limitations of non-invasive diagnostic tools. Liver biopsy remains the gold standard but is not suited for routine screening or clinical studies. Therefore, there is a great demand for accurate non-invasive screening tools that can not only diagnose but also stage NAFLD. This study aims to generate a large cohort of thoroughly characterized type 1 diabetes patients screened for NAFLD using multiple non-invasive tools including MRI, ultrasound, controlled attenuation parameter, and score panels. We aim to generate a biobank to promote a research collaboration network in the field of non-invasive diagnosis of NAFLD. A secondary endpoint is to investigate the potential correlation between the presence of NAFLD and the occurrence of micro-or macrovascular complications in patients with diabetes.

NAFLDType 1 DiabetesCardiovascular Diseases

University Hospital, Antwerp700 participantsStarted Sep 2018

Edegem, Antwerp, Belgium

COMPLETEDNA

Nutritional Prehabilitation Program and Cardiac Surgery Outcome in Pediatrics

NCT02475759

Nutritional Prehabilitation Program and Cardiac Surgery Outcome in Pediatrics. A randomized controlled trial.

Congenital Heart Disease

Ain Shams University52 participantsStarted Nov 2017

Cairo, Egypt

Prevalence, Incidence and Characteristics of NAFLD/NASH in Type 1 Diabetes Mellitus

Nutritional Prehabilitation Program and Cardiac Surgery Outcome in Pediatrics

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