Heart Disease Clinical Trials in Texas

Showing 221-240 of 301 trials

An Evaluation of Rigid Sternal Fixation in Supporting Bone Healing and Improving Postoperative Recovery

NCT01783483

The primary objective of this study is to evaluate sternal bone healing following a full median sternotomy versus standard of care for sternal closure with wire cerclage. Additional outcomes on post-operative pain and analgesic usage, patient function and quality of life, and complications will also be collected. A health economics study will also be conducted, in which cost and billing data will be collected from sites participating in this clinical study.

Coronary Artery DiseaseAngina PectorisCardiac Valve Disease

Zimmer Biomet236 participantsStarted Jan 2013

Jacksonville, Florida, United States • Orlando, Florida, United States • Atlanta, Georgia, United States +9 more locations

COMPLETEDPhase 313 miles

Effect of Pexelizumab on All-Cause Mortality and Myocardial Infarction in Patients Undergoing Coronary Artery Bypass Graft Surgery With Cardio-Pulmonary Bypass

NCT00048308

During a heart bypass procedure, a substance called "complement" is released by the body. This complement causes inflammation, which can lead to side effects such as chest pain, heart attacks, heart failure, or impairment of memory, language and motor skills. The purpose of this study is to find out if the study drug (pexelizumab), which blocks complement release, can reduce such side effects and be taken safely.

Cardio-pulmonary BypassCoronary Artery Bypass Graft

Alexion Pharmaceuticals, Inc.3,000 participantsStarted Jan 2002

Birmingham, Alabama, United States • Birmingham, Alabama, United States • Mobile, Alabama, United States +183 more locations

An Evaluation of Rigid Sternal Fixation in Supporting Bone Healing and Improving Postoperative Recovery

Effect of Pexelizumab on All-Cause Mortality and Myocardial Infarction in Patients Undergoing Coronary Artery Bypass Graft Surgery With Cardio-Pulmonary Bypass

Heart Disease Trials in Other Cities

A Phase II Study of the Safety and Efficacy of MPSK3169A in Patients With Coronary Heart Disease or High Risk of Coronary Heart Disease

Naltrexone/Bupropion Cardiovascular Outcomes Study

Safety and Efficacy of Mipomersen (ISIS 301012) As Add-on Therapy in High Risk Hypercholesterolemic Patients

Efficacy and Safety Study of ISIS 301012 (Mipomersen) as Add-on in Familial Hypercholesterolemic Patients With Coronary Artery Disease

TAXUS Libertē Post Approval Study

Does Prophylactic Coronary Artery Revascularization for High Risk Patients Reduce Long-term Risk of Mortality

A Study of RO4905417 in Patients Undergoing Coronary Artery Bypass Graft (CABG) Surgery

Safety and Tolerability of Initiating LCZ696 in Heart Failure Patients

Multi-center Assessment of Grafts in Coronaries: Long-term Evaluation of the C-Port Device

Randomized, Double-Blind, Placebo Controlled Study of the Short Term Clinical Effects of Tolvaptan in Patients Hospitalized for Worsening Heart Failure With Challenging Volume Management

Functional Impact of GLP-1 for Heart Failure Treatment (FIGHT)

Study To Evaluate D-Ribose For The Treatment of Congestive Heart Failure

Niacin Plus Statin to Prevent Vascular Events

GORE Flow Reversal System and GORE Embolic Filter Extension Study

Feasibility Study of BMAC Enhanced CABG

Comprehensive Rimonabant Evaluation Study of Cardiovascular ENDpoints and Outcomes

A Phase IIb Study to Investigate the Efficacy and Tolerability of Lower Doses Cinaciguat (25 µg/h, 10 µg/h) Given Intravenously to Patients With Acute Decompensated Chronic Congestive Heart Failure (ADHF)

Sensor Optimization of Cardiac Resynchronization Therapy Response

Other Conditions in Texas