Heart Disease Clinical Trials in Pittsburgh

Showing 261-280 of 455 trials

Remifentanil and Glycemic Response in Cardiac Surgery

NCT02349152

This study evaluates the effect of using remifentanil during cardiopulmonary bypass surgery to supress the hyperglycemic response in perioperative period. Half of the participants will receive continuous intravenous remifentanil during surgery, while the other half will receive intermittent intravenous fentanyl during surgery. Intermittent intravenous fentanyl administration is this institution's standard of care.

Heart DiseasesHyperglycemia

Kathirvel Subramaniam116 participantsStarted Jan 2016

Pittsburgh, Pennsylvania, United States

COMPLETEDPhase 3< 1 mile

A Study of RO4607381 in Stable Coronary Heart Disease Patients With Recent Acute Coronary Syndrome

NCT00658515

This study will evaluate the potential of RO4607381 to reduce cardiovascular morbidity and mortality in stable coronary heart disease patients with recent Acute Coronary Syndrome (ACS) and evaluate the long term safety profile of the drug. Eligible patients in stable condition will be randomized to receive either RO4607381 600mg po or placebo po, daily, together with a background of standard medication for ACS (including aspirin, antihypertensives and statins). The anticipated time on study treatment is 2+ years, and the target sample size is 15,600 individuals.

Coronary Heart Disease

Hoffmann-La Roche15,871 participantsStarted Apr 2008

Birmingham, Alabama, United States • Birmingham, Alabama, United States • Birmingham, Alabama, United States +1086 more locations

Remifentanil and Glycemic Response in Cardiac Surgery

A Study of RO4607381 in Stable Coronary Heart Disease Patients With Recent Acute Coronary Syndrome

Heart Disease Trials in Other Cities

Evaluation of the Safety and Effectiveness of the DuraHeart™ LVAS

HW006 LATERAL Thoracotomy

Predictors of Response to Biventricular Pacing in Heart Failure

The Evaluation of Bococizumab (PF-04950615; RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects

Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) in Patients With Hyperlipidemia and Statin Intolerant

Evaluation of Cardiac Compass With OptiVol in the Early Detection of Decompensation Events for Heart Failure

VITROS Immunodiagnostic Products NT-proBNP II

Patient and Provider Assessment of Lipid Management Registry

A Study of the Effect of Dalcetrapib on Artherosclerotic Disease in Patients With Coronary Artery Disease

Mitroflow DL Post Approval Study- North America

A Study to Assess the Effect of Intravenous Dose of (aMBMC) to Subjects With Non-ischemic Heart Failure

Correlation of SOZO BIS Measures With CardioMEMS PA Pressure

Integrated Tele-monitoring and Patient-centric Health Coaching Strategy in Patients Hospitalized With Heart Failure

Comparison of a Rivaroxaban-based Strategy With an Antiplatelet-based Strategy Following Successful TAVR for the Prevention of Leaflet Thickening and Reduced Leaflet Motion as Evaluated by Four-dimensional, Volume-rendered Computed Tomography (4DCT)

A Study of Dalcetrapib in Patients Hospitalized For An Acute Coronary Syndrome (Dal-ACUTE)

A Trial to Study Neladenoson Bialanate Over 20 Weeks in Patients With Chronic Heart Failure With Preserved Ejection Fraction

Functional Lesion Assessment of Intermediate Stenosis to Guide Revascularisation

e-NOBORI Observational Registry of Nobori DES

Other Conditions in Pittsburgh