Heart Disease Clinical Trials in Miami

Showing 61-80 of 227 trials

A Crossover Study of Patients with HF to Compare Natriuretic Effects of IR Torsemide Vs. ER Torsemide Over 12 Hrs

NCT06708611

This is a randomized double-blind crossover study of the patients with stable heart failure, who are taking a loop diuretic. During the study period, the participants' loop diuretics will be replaced by the equivalent dose of immediate release/extended release torsemide for one week. After a one week period, they will report to the site and will receive a single dose of either immediate release or extended release Torsemide. The sodium excretion will be measured for six hours after dosing and for an additional six hours after a high salt lunch.

Heart Failure

Sarfez Pharmaceuticals, Inc.5 participantsStarted Jan 2025

Miami, Florida, United States

COMPLETEDPhase 2< 1 mile

A Study of Mavacamten in Participants With HFpEF and Elevation of NT-proBNP With or Without Elevation of cTnT

NCT04766892

This is a Phase 2a proof-of-concept study to assess safety, tolerability, and preliminary efficacy of mavacamten treatment on biomarker levels in participants with heart failure with preserved ejection fraction (HFpEF) and elevation of NT-proBNP with or without elevation of cTnT. Data from this study will inform future study designs of mavacamten in patients with HFpEF.

Heart Failure With Preserved Ejection Fraction

Bristol-Myers Squibb30 participantsStarted Mar 2021

Birmingham, Alabama, United States • Phoenix, Arizona, United States • Tucson, Arizona, United States +18 more locations

A Crossover Study of Patients with HF to Compare Natriuretic Effects of IR Torsemide Vs. ER Torsemide Over 12 Hrs

A Study of Mavacamten in Participants With HFpEF and Elevation of NT-proBNP With or Without Elevation of cTnT

Heart Disease Trials in Other Cities

PROACTIVE-HF IDE Trial Heart Failure NYHA Class III

Intracardiac CrYoablation for AtrioVentricular Nodal Reentrant Tachycardia

Benefits of Microcor in Ambulatory Decompensated Heart Failure

Effects of NT-0796 in Obese Participants at Risk of Cardiovascular Disease

Caffeine's Effect on Regadenoson Administration With Single Photon Emission Computed Tomography (SPECT) Myocardial Perfusion Imaging (MPI)

Benefits of µCor in Ambulatory Decompensated Heart Failure

A CCTA Imaging Trial to Evaluate the Effect of Obicetrapib/Ezetimibe on Coronary Plaque

Safety and Efficacy Study of reSept ASD Occluder for Treating Secundum ASD

Distal Evaluation of Functional Performance with Intravascular Sensors to Assess the Narrowing Effect: Guided Physiologic Stenting

Utility of Donor-Derived Cell Free DNA in Association With Gene Expression Profiling

FUnctional diagnoSIs of corONary Stenosis (FUSION)

Efficacy and Safety of MEDI6570 in Patients With a History of Myocardial Infarction

Off-pump Versus On-pump Coronary Artery Bypass Grafting in Frail Patients

A Study to Evaluate Whether Macitentan is an Effective and Safe Treatment for Patients With Heart Failure With Preserved Ejection Fraction and Pulmonary Vascular Disease

Clinical Study Assessing the Efficacy and Safety of Macitentan in Fontan-palliated Subjects

Guideline Directed Medical Therapy (GDMT) Optimization and Adherence Longitudinal Study for Heart Failure.

Long-term Efficacy and Safety of OLE LIB003 in HoFH, HeFH, and High-risk CVD Patients Requiring Further LDL-C Reduction

Multi-Center Evaluation of Feasibility of SPECT Measurement of Myocardial Blood Flow and Reserve

Other Conditions in Miami