Heart Disease Clinical Trials in Cleveland

Showing 321-340 of 448 trials

Preliminary Assessment of Added Diagnostic Value of Dual Energy CT Images Using Data Acquired on a Spectral Detector CT

NCT02760706

Study hypothesis: Post-processed SDCT images provide additional diagnostic value over conventional CT datasets. The CT examination would be a clinically-necessary, standard-of-care CT performed as per the clinical indication. The protocol and scan parameters for the CT exam will be similar to that of an equivalent scan performed with any other CT scanner. There would be no additional scanner of injection of any drug specifically for the study. The conventional CT images generated by the scanner will be used for clinical purposes as routinely practiced.

Compare Image Quality Between SDCT and Conventional CT Images of Any Tissue Lesion, Determine Optimal Monochromatic Energy Level for a Coronary Artery Image

Philips Healthcare303 participantsStarted Oct 2013

Cleveland, Ohio, United States

TERMINATEDPhase 4< 1 mile

Naltrexone/Bupropion Cardiovascular Outcomes Study

NCT02638129

The purpose of this study is to evaluate cardiovascular (CV) safety of naltrexone hydrochloride (HCl) and bupropion HCl extended release combination (NB) compared with placebo and rule out excess risk of major adverse cardiovascular events (MACE) when given in combination with standard of care in overweight and obese participants with documented history of CV disease.

ObesityCardiovascular Diseases

Orexigen Therapeutics, Inc67 participantsStarted Jan 2016

Alexander City, Alabama, United States • Auburn, Alabama, United States • Birmingham, Alabama, United States +136 more locations

Preliminary Assessment of Added Diagnostic Value of Dual Energy CT Images Using Data Acquired on a Spectral Detector CT

Naltrexone/Bupropion Cardiovascular Outcomes Study

Heart Disease Trials in Other Cities

Effect of Pexelizumab on All-Cause Mortality and Myocardial Infarction in Patients Undergoing Coronary Artery Bypass Graft Surgery With Cardio-Pulmonary Bypass

Functional Impact of GLP-1 for Heart Failure Treatment (FIGHT)

Get Going: Accelerometer-Based Intervention to Promote Physical Activity in Frail Older Adults

Assessment of Catheter-based Interrogation and Standard Techniques for Fractional Flow Reserve Measurement

A Dose-Defining Study of CXL-1020 in Patients With Systolic Heart Failure

Safety and Efficacy of Mipomersen (ISIS 301012) As Add-on Therapy in High Risk Hypercholesterolemic Patients

Efficacy and Safety Study of ISIS 301012 (Mipomersen) as Add-on in Familial Hypercholesterolemic Patients With Coronary Artery Disease

Randomized, Double-Blind, Placebo Controlled Study of the Short Term Clinical Effects of Tolvaptan in Patients Hospitalized for Worsening Heart Failure With Challenging Volume Management

Evaluation of Vepoloxamer in Chronic Heart Failure

Blood Collection of Patient Presenting in the ED and Prescribed a BNP

A Study of RO4905417 in Patients Undergoing Coronary Artery Bypass Graft (CABG) Surgery

A Phase II Study of the Safety and Efficacy of MPSK3169A in Patients With Coronary Heart Disease or High Risk of Coronary Heart Disease

Targeting Acute Congestion With Tolvaptan in Congestive Heart Failure

Sensor Optimization of Cardiac Resynchronization Therapy Response

Study To Evaluate D-Ribose For The Treatment of Congestive Heart Failure

Educational Program for Various Health Literacy Levels to Improve the Health of Individuals With Heart Failure

Comprehensive Rimonabant Evaluation Study of Cardiovascular ENDpoints and Outcomes

Pharmacodynamic and Pharmacokinetic Study of BiDil Extended-release Capsules and Commercial BiDil Tablets

Other Conditions in Cleveland