Heart Disease Clinical Trials in Boston

Showing 101-120 of 452 trials

Polygenic Risk-based Detection of Subclinical Coronary Atherosclerosis and Intervention With Statin and Colchicine

NCT05850091

The goal of this double-blind randomized controlled trial is to determine how treatment with high intensity statin, low-dose colchicine, and their combination modulates progression and composition of coronary atherosclerosis in individuals with high polygenic risk for coronary artery disease.

Coronary Artery Disease

Massachusetts General Hospital200 participantsStarted Dec 2023

Boston, Massachusetts, United States

Active Not Recruiting< 1 mile

Long Term Follow Up for CTSN Mitral Valve Repair Studies

NCT03066050

This study is a continuation of two previous studies --- the Severe Ischemic Mitral Regurgitation (SMR) Trial (NCT00807040) and the Moderate Ischemic Mitral regurgitation (MMR) Trial (NCT00806988) --- to learn more about patients' health 5-10 years after their mitral valve surgeries. The investigators will collect long-term health information on SMR and MMR trial participants using electronic medical records, patient and/or family input, public records, and healthcare- and vital status-related databases.

Mitral Valve InsufficiencyCoronary Artery Disease

Icahn School of Medicine at Mount Sinai368 participantsStarted May 2017

Los Angeles, California, United States • Atlanta, Georgia, United States • Baltimore, Maryland, United States +21 more locations

Polygenic Risk-based Detection of Subclinical Coronary Atherosclerosis and Intervention With Statin and Colchicine

Long Term Follow Up for CTSN Mitral Valve Repair Studies

Heart Disease Trials in Other Cities

Global Utilization And Registry Database for Improved heArt preservatioN

Mindful Steps 2.0: Promoting Physical Activity in Patients With COPD and HF

SURPASS Impella 5.5 Study

Effects of Gender-Affirming Hormone Therapy Among Transgender Women

Safety and Efficacy Study of reSept ASD Occluder for Treating Secundum ASD

Predictive Value of Coronary Heart Disease (CHD) Biomarkers for CHD Death

A Study to Evaluate Whether Macitentan is an Effective and Safe Treatment for Patients With Heart Failure With Preserved Ejection Fraction and Pulmonary Vascular Disease

Clinical Study Assessing the Efficacy and Safety of Macitentan in Fontan-palliated Subjects

A Study of Retatrutide (LY3437943) in Participants With Obesity and Cardiovascular Disease

Optisure Lead Post Approval Study

Rehabilitation at Home Using Mobile Health In Older Adults After Hospitalization for Ischemic Heart Disease

Magna® Mitral Pericardial Bioprostheses Post-Approval Study Protocol

RADIQAL Study (Radiation Dose and Image Quality Trial)

Cardiac Resynchronization Therapy in Previously Untreatable and High Risk Upgrade Patients

Conduction System Pacing Optimized Therapy

Imaging Study of Allocation of Pacing Targets in Cardiac Resynchronization Therapy

Multi-Center Evaluation of Feasibility of SPECT Measurement of Myocardial Blood Flow and Reserve

Abbott Vascular Medical Device Registry

Other Conditions in Boston