Heart Disease Clinical Trials in Baltimore

Showing 181-200 of 505 trials

Identifying and Facilitating Ventricular Recovery on Mechanical Support

NCT00687856

Heart failure is a progressive disorder in which the weakened heart is not able to efficiently pump blood throughout the body. When the body's cells do not receive enough blood, this can result in fatigue, shortness of breath, and difficulty carrying out daily activities. The left ventricular assist device (LVAD) is a device that is used to provide mechanical circulatory support to patients with end-stage heart failure who are awaiting heart transplants. Although LVAD support helps maintain the pumping ability of the heart and dramatically improves heart failure symptoms, the quality of life with LVAD support is far from ideal. It has been shown that LVAD support in selected patients may restore the failing heart enough to eliminate the need for heart transplant, but more information is needed to assess heart recovery and to guide weaning of LVAD support. Using data collected from patients who have undergone LVAD implantation, this study will attempt to better assess heart recovery and to generate criteria for identifying patients eligible for the removal of LVAD support.

Heart Failure

University of Pittsburgh211 participantsStarted Apr 2008

Baltimore, Maryland, United States • Ann Arbor, Michigan, United States • Oklahoma City, Oklahoma, United States +2 more locations

COMPLETEDPhase 3< 1 mile

Study to Assess the Safety and Tolerability of IV Tonapofylline in Subjects With Acute Decompensated Heart Failure (ADHF) and Renal Insufficiency

NCT00709865

The purpose of the current study is to assess the safety and tolerability of intravenous tonapofylline.

Renal InsufficiencyCongestive Heart Failure

Biogen420 participantsStarted Jul 2008

Huntsville, Alabama, United States • Mobile, Alabama, United States • Fort Smith, Arkansas, United States +186 more locations

Identifying and Facilitating Ventricular Recovery on Mechanical Support

Study to Assess the Safety and Tolerability of IV Tonapofylline in Subjects With Acute Decompensated Heart Failure (ADHF) and Renal Insufficiency

Heart Disease Trials in Other Cities

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care

Multi-center Prospective Study to Evaluate Outcomes of the Moderate to Severely Calcified Coronary Lesions (MACE)

Cardiovascular Disease in HIV and Hepatitis C: Risk Outcomes After Hepatitis C Eradication

Genomic Response Analysis of Heart Failure Therapy in African Americans

Pilot Study to Evaluate the Effect of Nicotinamide Riboside on Immune Activation in Psoriasis

Evaluation of Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty Technique Prior to Implantation of Drug-Eluting StEnts: The ECLIPSE Trial

Clinical Use Cases Assessment of the Gabi System in Young Children With Underlying Medical Conditions (BRIDGE Study)

Telemonitoring to Treat Group 2 Pulmonary Hypertension

A Clinical Trial to Confirm Safety & Effectiveness of the SYNERGY 4.50 mm and 5.00 mm Stent for Treatment of Atherosclerotic Lesion(s)

The Salty Gut: Effects of High Dietary Salt Intake on the Gut Microbiota

An International Study to Evaluate Diagnostic Efficacy of Flurpiridaz (18F) Injection PET MPI in the Detection of Coronary Artery Disease (CAD)

Left Atrial Pressure Monitoring to Optimize Heart Failure Therapy

ANTHEM-HFrEF Pivotal Study

A Clinical Evaluation of the MINI TREK RX 1.20 mm Coronary Dilatation Catheter in Stenotic Lesions

Evaluate the Safety and Efficacy of OAS in Treating Severely Calcified Coronary Lesions

Study of Verinurad in Heart Failure With Preserved Ejection Fraction

Single-Ascending Dose Study of JK07 in Subjects With HFpEF

Resynchronization/Defibrillation for Ambulatory Heart Failure Trial

Other Conditions in Baltimore