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Clareo Health | Epilepsy Clinical Trials in Philadelphia | 133 Studies

Clinical Trials EpilepsyPhiladelphia

Epilepsy Clinical Trials in Philadelphia

Find 133 clinical trials for epilepsy near Philadelphia, Pennsylvania. Connect with research centers in your area.

All Epilepsy trials nationwide All trials in Philadelphia

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 1-20 of 133 trials

RecruitingA Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet SyndromeThis is a multicenter, Phase 3, randomized, double-blind, placebo-controlled study designed to evaluate the efficacy and safety of clemizole hydrochloride (EPX-100) as adjunctive…NCT04462770·Birmingham, Alabama and 67 others

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Data from ClinicalTrials.govTerms

CompletedRandomized Therapy In Status EpilepticusThis study evaluated the effectiveness and safety of an investigational product (IP), intravenous (IV) ganaxolone, to treat participants with status epilepticus (SE).NCT04391569·Birmingham, Alabama and 73 others

RecruitingA Long-term Study of the Safety and Effectiveness of RAP-219 in Adults With Focal Onset SeizuresThis is a clinical research study for an investigational drug called RAP-219 in patients with Refractory Focal Epilepsy.NCT07219407·Boise, Idaho and 6 others

CompletedA 12-Month Study To Evaluate The Safety And Tolerability Of Pregabalin As Add-On Therapy In Pediatric Subjects 1 Month To 16 Years Of Age With Partial Onset Seizures And Pediatric And Adult Subjects 5 To 65 Years Of Age With Primary Generalized Tonic-Clonic SeizuresStudy A0081106 is a 12-month open-label study to evaluate the long term safety and tolerability of pregabalin as add-on therapy in pediatric subjects 1 month to 16 years of age…NCT01463306·Tucson, Arizona and 150 others

CompletedLevetiracetam: The Anti-Convulsant of Choice for Elderly Patients With DementiaElderly persons with dementia are at risk for seizures, however, traditional anticonvulsants are poorly tolerated in this population.NCT01318408·Philadelphia, Pennsylvania

TerminatedBioavailability, Safety and Tolerability of Diazepam Nasal Spray Versus Diazepam Rectal Gel (Diastat®)This is a multi-center, open-label, crossover, pharmacokinetic, bio-availability study involving adolescents and adults with refractory (drug-resistant) epilepsy.NCT02474407·Little Rock, Arkansas and 21 others

CompletedDetermine Safety and Efficacy of Long-term Oral Lacosamide in Patients With Partial SeizuresThe purpose of this trial is to determine whether lacosamide is safe and effective for long-term use in patients with partial-seizures from epilepsyNCT00522275·Birmingham, Alabama and 59 others

CompletedTo Determine Tolerability and Efficacy of Long-term Oral Lacosamide in Patients With Partial SeizuresThe purpose of this trial is to determine whether lacosamide is safe and effective for long-term use in patients with partial-seizures from epilepsy.NCT00552305·Birmingham, Alabama and 58 others

CompletedStudy Evaluating LAMICTAL Extended-Release Therapy Added To Current Seizure Treatments In Patients With Partial SeizuresThis study is being conducted to compare the efficacy and safety of LAMICTAL (lamotrigine) extended-release with placebo in the treatment of partial seizures.NCT00113165·Anniston, Alabama and 147 others

CompletedProgesterone vs Placebo Therapy for Women With EpilepsyThe purpose of this investigation was to determine if cyclic adjunctive progesterone supplement is superior to placebo in the treatment of intractable seizures in women with and…NCT00029536·Los Angeles, California and 14 others

CompletedChildhood Absence Epilepsy Rx PK-PD-Pharmacogenetics StudyThe purpose of this study is to determine the best initial treatment for childhood absence epilepsy.NCT00088452·Birmingham, Alabama and 30 others

CompletedSafety and Pharmacokinetic Study of YKP3089 as Adjunctive Therapy in Subjects With Partial Onset SeizuresThis is a multicenter, open label study to assess the safety and pharmacokinetics of YKP3089 as adjunctive therapy in subjects with partial onset seizures.NCT02535091·Phoenix, Arizona and 120 others

RecruitingProspective Natural History Study of POLG DiseaseThe PIONEER study is a prospective, natural history study dedicated to characterizing the clinical progression of POLG-related disorders.NCT07775872·San Diego, California and 20 others

CompletedStudy to Investigate Dosage, Efficacy, and Safety of Fycompa in Routine Clinical Care of Patients With EpilepsyThis study is conducted to assess the retention rate of Fycompa when given in routine clinical care.NCT03208660·Phoenix, Arizona and 43 others

CompletedConversion To Monotherapy With Lamictal Extended Release Tablets For Treatment Of Partial EpilepsyThis study is being conducted to determine the effectiveness of a lower monotherapy dose of lamotrigine than that currently approved.NCT00355082·Alabaster, Alabama and 102 others

WithdrawnENACT: A Study of ENX-101 as Adjunctive Treatment in Patients With Focal SeizuresThe ENACT trial is designed to evaluate the efficacy and safety of ENX-101 administered adjunctively to current therapy in reducing seizure frequency in patients diagnosed with…NCT05481905·Phoenix, Arizona and 37 others

CompletedA 19-week Cognition Study of Levetiracetam in Children With Partial Onset SeizuresA 12-week Evaluation Period will be used to characterize potential cognitive and neuropsychological effects of LEV (20 - 60 mg/kg/day), as adjunctive treatment in children 4 - 16…NCT00105040·Birmingham, Alabama and 44 others

RecruitingRENAISSANCE 2: SPN-817 Phase 2, Double-Blind, Placebo-Controlled Study in Adults With Focal Onset SeizuresThis is a Phase 2 double-blind, randomized, placebo-controlled, multicenter, parallel-group study to evaluate the efficacy, safety, and tolerability of SPN-817 in adults with…NCT06798896·Phoenix, Arizona and 62 others

TerminatedCannabidiol Oral Solution in Pediatric Participants With Treatment-Resistant Childhood Absence SeizuresThe primary purpose of this study is to assess the efficacy of Cannabidiol Oral Solution in the treatment of pediatric participants with treatment-resistant childhood absence…NCT03336242·Miami, Florida and 10 others

CompletedStudy Evaluating LAMICTAL Extended-Release Therapy Added To Current Seizure Treatments In Patients With Primary Generalized Tonic-Clonic Seizures (PGTC) SeizuresThis study is being conducted to compare the efficacy and safety of LAMICTAL (lamotrigine) extended-release with placebo in the treatment of Primary Generalized Tonic-Clonic…NCT00104416·Anniston, Alabama and 145 others

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