Diabetes Clinical Trials in Cleveland

Showing 141-160 of 517 trials

Bariatric Surgery-Induced Shift in Gut Microbiome and NAFLD

NCT04263376

This study is designed as a prospective pilot study for longitudinal assessment of fecal microbiome related to medical and surgical weight loss. The investigators follow the standard of care for perioperative and intraoperative management of study participants. The only addition to the standard of care protocol will be collection of fecal samples at 3 time points. This will enable investigators to compare changes in and effects by microbiota after low-calorie diet versus after bariatric surgery .

ObesityDiabetes Mellitus, Type 2NAFLD

The Cleveland Clinic18 participantsStarted Apr 2019

Cleveland, Ohio, United States

COMPLETEDPhase 2< 1 mile

Hydroxychloroquine and Metabolic Outcomes in Patients Undergoing TPAIT

NCT03283566

This will be a pilot, 12-month phase II, open label, randomized, two-arm, single-blinded, placebo-controlled, parallel clinical trial of individuals undergoing TPAIT (Total Pancreatectomy and Autologous Islet Transplantation) for treatment of chronic pancreatitis (CP). The two study arms consist of HCQ-treated (Hydroxychloroquine) and placebo-treated individuals. The purpose of this study is to investigate the effects of HCQ administration compared to placebo on islet cell function post-autologous transplantation.

Chronic PancreatitisInsulin Dependent Diabetes

The Cleveland Clinic9 participantsStarted Oct 2017

Cleveland, Ohio, United States

COMPLETEDPhase 3< 1 mile

Non-inferiority Study to Compare the Efficacy and Safety of Mylan's Insulin Glargine With Lantus® in Type 2 Diabetes Mellitus Patients (INSTRIDE 2)

NCT02227875

To test whether Mylan's insulin glargine once daily is non-inferior to Lantus® once daily (both administered in combination with other anti-diabetic drugs) based on the change in HbA1c from baseline to 24 weeks

Type 2 Diabetes

Mylan Inc.560 participantsStarted Aug 2014

Chandler, Arizona, United States • Bell Gardens, California, United States • Fresno, California, United States +117 more locations

Bariatric Surgery-Induced Shift in Gut Microbiome and NAFLD

Hydroxychloroquine and Metabolic Outcomes in Patients Undergoing TPAIT

Non-inferiority Study to Compare the Efficacy and Safety of Mylan's Insulin Glargine With Lantus® in Type 2 Diabetes Mellitus Patients (INSTRIDE 2)

Diabetes Trials in Other Cities

Mylan Insulin Aspart Study

Arts & Health Education to Improve Health, Resilience, and Well-Being

Efficacy and Safety of Oral Semaglutide Versus Placebo in Subjects With Type 2 Diabetes Mellitus Treated With Diet and Exercise Only

Comparison of a New Formulation of Insulin Glargine With Lantus in Patients With Type 2 Diabetes Mellitus on Basal Plus Mealtime Insulin

Non-inferiority Study to Compare the Efficacy and Safety of Mylan's Insulin Glargine With Lantus® in Type 1 Diabetes Mellitus Patients (INSTRIDE 1)

Effect of Sotagliflozin on Cardiovascular Events in Participants With Type 2 Diabetes Post Worsening Heart Failure (SOLOIST-WHF Trial)

A Study to Test Whether Different Doses of BI 456906 Are Effective in Treating Adults With Type 2 Diabetes.

Efficacy and Safety of Oral Semaglutide Versus Liraglutide and Versus Placebo in Subjects With Type 2 Diabetes Mellitus

A Study of Dulaglutide (LY2189265) in Children and Adolescents With Type 2 Diabetes

A Trial of INS068 in Patients With Type 2 Diabetes Not Adequately Controlled With One or Two Oral Antidiabetics

Comparison of SAR341402 to NovoLog/NovoRapid in Adult Patients With Diabetes Mellitus Also Using Insulin Glargine

A Phase 2 Study of LY3209590 in Participants With Type 2 Diabetes Mellitus

Comparison of the Safety and Efficacy of HOE901-U300 With Lantus in Children and Adolescents With Type 1 Diabetes Mellitus

The International Diabetes Closed Loop (iDCL) Trial: Protocol 1

Multicenter Endoscopic Sleeve Gastrectomy (ESG) Trial (MERIT Trial)

The International Diabetes Closed Loop (iDCL) Trial: Protocol 4

Twelve -Month Study Observing How Insulin-naïve Patients With Type 2 Diabetes Mellitus Manage Diabetes Using Toujeo® After Oral Antidiabetic Drug Failure, the Side Effect of Toujeo®, and The Cost.

Other Conditions in Cleveland