COVID-19 Clinical Trials in Chicago

Showing 1-20 of 166 trials

Cognitive-Sensorimotor Function in Long-COVID

NCT06850350

Growing evidence indicates that many people who have chronic post-acute sequelae of SARS-CoV-2 infection (PASC) will experience ongoing neurological and musculoskeletal impairment that can affect gait and balance. Identifying the factors contributing to these impairments and how they influence functional mobility is the first step towards creating effective evaluation and treatment protocols. In this study the investigators will examine cognition, vision, proprioception, muscle strength, gait and balance in persons with and without PASC to understand how PASC may impact functional mobility through a cognitive-sensorimotor lens. Gait and balance will be studied in environments that stress cognitive and sensory abilities. Study outcomes will be critical for the development of evidence-based Veteran Health Administration diagnostic and standard-of-care protocols to address gait and balance dysfunction in Veterans with PASC for restoring their functional mobility and independence.

Post-acute Sequelae of SARS-CoV-2 Infection

VA Office of Research and Development136 participantsStarted Apr 2026

Chicago, Illinois, United States

RECRUITINGPhase 32.2 miles

Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVID

NCT06631287

The overarching goal of this study is to determine if baricitinib, as compared to placebo, will improve neurocognitive function, along with measures of physical function, quality of life, post-exertional malaise, effect of breathlessness on daily activities, post-COVID-19 symptom burden, and biomarkers of inflammation and viral measures, in participants with Long COVID.

Long COVIDSars-CoV-2 InfectionCoronavirus Infections+1 more

Wes Ely550 participantsStarted Oct 2024

Tucson, Arizona, United States • Los Angeles, California, United States • San Francisco, California, United States +13 more locations

Cognitive-Sensorimotor Function in Long-COVID

Randomized Double-Blind Placebo-Controlled Trial EValuating Baricitinib on PERSistent NEurologic and Cardiopulmonary Symptoms of Long COVID

COVID-19 Trials in Other Cities

Improving Attention in Individuals With Long COVID-19

I-SPY COVID-19 TRIAL: An Adaptive Platform Trial for Critically Ill Patients

Dime La VerDAD: Verify, Debunk, and Disseminate

Reparixin add-on Therapy to Standard Care to Limit Progression in Pts With COVID19 & Other Community Acquired Pneumonia

A Study to Learn About a COVID-19 Vaccine in Healthy Adults 50 Through 64 Years of Age

RECOVER-VITAL: Platform Protocol to Measure the Effects of Antiviral Therapies on Long COVID Symptoms

Low-Dose Radiotherapy For Patients With SARS-COV-2 (COVID-19) Pneumonia

Understanding the Long-term Impact of COVID on Children and Families

Study of VYD2311 for the Prevention of COVID-19

Safety and Immunogenicity of NVX-CoV2705

A Study to Learn About BNT162b2 (LP.8.1)-Adapted Vaccine Against SARS-CoV-2 in Children 5 Through 11 Years of Age That Are Considered at Higher Risk of Severe COVID-19

A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease

Chronic Lung Disease and COVID-19: Understanding Severity, Recovery and Rehabilitation Needs

A Study to Learn About Variant-Adapted COVID-19 RNA Vaccine Candidate(s) in Healthy Children

A Safety and Immunogenicity Trial of Boost-2867 Vaccine, Via Intranasal and Intramuscular Routes

Evaluation of COVID-19 and Flu A/B 3 in 1 Combo Rapid Test

Immune-mediated Pathogenic Mechanisms of Neuro-PASC in Veterans

ABX464 in Treating Inflammation and Preventing Acute Respiratory Failure in Patients With COVID-19

Other Conditions in Chicago