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Clareo Health | Colorectal Cancer Clinical Trials in Philadelphia | 277 Studies

Clinical Trials Colorectal CancerPhiladelphia

Colorectal Cancer Clinical Trials in Philadelphia

Find 277 clinical trials for colorectal cancer near Philadelphia, Pennsylvania. Connect with research centers in your area.

All Colorectal Cancer trials nationwide All trials in Philadelphia

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 41-60 of 277 trials

CompletedReducing Colorectal Cancer Death Through Mailed Outreach ScreeningThe main study aim is to develop, implement and disseminate a pilot population-based mailed FIT outreach screening program in the Philadelphia VA Medical Center that does not rely…NCT02584998·Philadelphia, Pennsylvania CompletedA Study of XmAb®23104 in Subjects With Selected Advanced Solid Tumors (DUET-3)This is a Phase 1, multiple dose, ascending dose escalation study to define a MTD/RD and regimen of XmAb23104, to describe safety and tolerability, to assess PK and…NCT03752398·San Diego, California and 17 others

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Data from ClinicalTrials.govTerms

RecruitingThe Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)The Phase 2 monotherapy portion of this study is currently enrolling and will evaluate the efficacy and safety of PC14586 (INN rezatapopt) in participants with locally advanced or…NCT04585750·Irvine, California and 75 others

RecruitingFT836 With or Without Chemotherapy and/or Monoclonal Antibodies, in Participants With Advanced Solid TumorsThis is a Phase 1 study of FT836 administered in participants with advanced solid tumors.NCT07216105·La Jolla, California and 4 others

CompletedPreliminary Evaluation of Septin9 in Patients With Hereditary Colon Cancer SyndromesThis is an observational, case-control study evaluating the quantitative level of Septin9 in plasma pre- and post-colectomy in hereditary colorectal cancer (CRC) syndrome patients…NCT02198092·Philadelphia, Pennsylvania

CompletedA Safety and Efficacy Study of ZW25 (Zanidatamab) Plus Combination Chemotherapy in HER2-expressing Gastrointestinal Cancers, Including Gastroesophageal Adenocarcinoma, Biliary Tract Cancer, and Colorectal CancerThis is a multicenter, global, Phase 2, open-label, 2-part, first-line study to investigate the safety, tolerability, and anti-tumor activity of ZW25 (zanidatamab) plus standard…NCT03929666·Los Angeles, California and 22 others

CompletedStudy of Oxaliplatin/5-FU/Leucovorin Plus Vatalanib Versus Oxaliplatin/5-FU/Leucovorin in Patients With Previously Treated Metastatic Colorectal CancerThe purpose of this study is to compare treatment with oxaliplatin/5-FU/leucovorin plus vatalanib versus oxaliplatin/5-FU/leucovorin plus placebo in patients with colorectal…NCT00056446·Huntsville, Alabama and 250 others

Active not recruitingCancer Preventive Vaccine Nous-209 for Lynch Syndrome PatientsThis phase Ib/II trial evaluates the safety and effect of the Nous-209 vaccine in Lynch syndrome patients.NCT05078866·Duarte, California and 3 others

UnknownStudy of Neratinib +Trastuzumab or Neratinib + Cetuximab in Patients With KRAS/NRAS/BRAF/PIK3CA Wild-Type Metastatic Colorectal Cancer by HER2 StatusThis is a phase II trial to examine the efficacy of neratinib plus trastuzumab or neratinib plus cetuximab in patients with "quadruple wild-type" (all RAS/NRAS/BRAF/PIK3CA…NCT03457896·Anaheim, California and 47 others

TerminatedA Study of Xeloda (Capecitabine) in Combination With Avastin + Short Course Chemotherapy in Patients With Metastatic Colorectal CancerThis 2-arm study was designed to evaluate the efficacy and safety of 2 treatment regimens of Xeloda and Avastin, with either irinotecan or oxaliplatin administered for the first…NCT00642603·PARK Springs, Arizona and 75 others

CompletedA Volume, Motion, and Anatomically Adaptive Approach to Photon and Proton Beam RadiotherapyThis pilot study will determine changes over time in tumor volume/motion \& patient anatomy, as well as dose distributions to normal organs.NCT02130427·Philadelphia, Pennsylvania

CompletedTrial Of Irinotecan In Combination With Three Methods Of Administration Of Fluoropyrimidine.This study compares in the first study period combination of Irinotecan with three different methods of administration by Fluoropyrimidine. (ie. infusion, bolus and oral).NCT00101686·Birmgingham, Alabama and 174 others

Active not recruitingStudy of DECOY20 With or Without Tislelizumab in Patients With Advanced Solid TumorsINDP-D101 is a Phase 1/2, open-label, multi-center, dose escalation and expansion study evaluating the safety, tolerability and clinical activity of Decoy20 as monotherapy and in…NCT05651022·Los Angeles, California and 11 others

Active not recruitingA Phase 1/2 Study to Evaluate CHM-2101, an Autologous Cadherin 17 Chimeric Antigen Receptor (CAR) T Cell TherapyThe goal of this clinical trial is to evaluate CHM-2101, an autologous CDH17 CAR T-cell therapy for the treatment of advanced gastrointestinal (GI) cancers that are relapsed or…NCT06055439·Atlanta, Georgia and 3 others

TerminatedA Phase III Study of Xilonix in Patients With Advanced Colorectal CancerThe purpose of this study is to determine if the True Human Monoclonal antibody Xilonix (MABp1) can prolong the life of colorectal carcinoma patients that are refractory to…NCT01767857·Birmingham, Alabama and 112 others

RecruitingPhase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal CancerA Randomized, Active-Controlled, Double-blind, Multicenter, Phase 3 Clinical Study of Ivonescimab in Combination with mFOLFOX6 (Oxaliplatin, Leucovorin and 5-Fluorouracil) versus…NCT07228832·Mobile, Alabama and 235 others

CompletedEfficacy Study of [F-18]RGD-K5 Positron Emission Tomography (PET) as a Tool to Monitor Response to an Anti-angiogenic DrugA Pilot Phase II Study The primary objective for this study is: * To explore the usefulness of \[F-18\]RGD-K5 PET/CT to predict efficacy or early response to Avastin® (the…NCT00988936·Irvine, California and 7 others

CompletedInvestigating Cabozantinib in Patients With Refractory Metastatic Colorectal CancerThis study seeks to use Cabozantinib to treat those with Metastatic Colorectal Cancer who have not previously responded to treatment.NCT03542877·Tucson, Arizona and 9 others

RecruitingTCR1188-ABC Cells in KRAS-mutated CancersThis is a Phase I, open-label dose finding study to assess the safety, manufacturing feasibility, and preliminary efficacy of TCR1188-ABC cells in patients with KRAS-mutated…NCT07594067·Philadelphia, Pennsylvania

RecruitingA Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D MutationThis study is conducted to determine the safety and tolerability of INCB161734 as a single agent or in combination with other anticancer therapies.NCT06179160·Phoenix, Arizona and 33 others

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Other Conditions in Philadelphia

Breast Cancer Lung Cancer Prostate Cancer Melanoma Leukemia Lymphoma