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Clareo Health | Brain Cancer Clinical Trials | 951 Studies Recruiting

Clinical TrialsBrain Cancer

Brain Cancer Clinical Trials

Browse 951 clinical trials for brain cancer. Find studies that match your criteria and connect with research centers.

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Showing 421-440 of 951 trials

TerminatedDetermining Dose of Regadenoson Most Likely to Transiently Alter the Integrity of the Blood-Brain Barrier in Patients With High Grade Gliomasenroll patients with histologically confirmed high-grade gliomas to evaluate the ability of regadenoson to transiently disrupt a relatively intact blood-brain barrier (BBB)…NCT03971734·Baltimore, Maryland and 1 other WithdrawnC11-Sodium Acetate PET/CT Imaging Evaluation in Brain Glioma, Post Therapy Necrosis and Pseudo-progressionThis study will investigate how well Carbon Acetate PET/CT imaging helps to correctly identify recurrent tumor versus post treatment effects (radionecrosis) in patients with…NCT01961934·Phoenix, Arizona Not yet recruitingFPS-ZM1 With or Without Dexamethasone for Controlling Post Operative Cerebral Edema in Patients With GlioblastomaThis phase I trial tests the safety, side effects, best dose and how well FPS-ZM1 works for controlling post operative cerebral edema in patients with glioblastoma.NCT07791264·Duarte, California CompletedCombination Chemotherapy and Radiation Therapy in Treating Younger Patients Who Are Undergoing an Autologous Stem Cell Transplant for Newly Diagnosed GliomasRATIONALE: Drugs used in chemotherapy, such as temozolomide, busulfan, and O6-benzylguanine, work in different ways to stop the growth of tumor cells, either by killing the cells…NCT00253487

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glioblastomatrials gliomatrials brain tumortrials

Data from ClinicalTrials.govTerms

CompletedRadiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Brain CancersRATIONALE: Radiolabeled monoclonal antibodies can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells.NCT00002752·Durham, North Carolina

CompletedMRI-Guided Laser Surgery and Doxorubicin Hydrochloride in Treating Patients With Recurrent Glioblastoma MultiformeThis pilot clinical trial studies magnetic resonance imaging (MRI)-guided laser surgery (MLA) and doxorubicin hydrochloride in treating patients with recurrent glioblastoma…NCT01851733·St Louis, Missouri

Not yet recruitingBrain Radiotherapy Imaging for High-grade Glioma Using Hypoxia Targeting Through Oxygen-Enhanced ResponseHigh-grade gliomas (HGGs) are the most common type of brain cancer in adults. Life expectancy for patients with HGGs is low.NCT07670455

UnknownThe PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology)The PIONEER Initiative stands for Precision Insights On N-of-1 Ex vivo Effectiveness Research.NCT03896958·Gainesville, Georgia

CompletedPh. I Temozolomide + O6-BG + Irinotecan in Treatment of Pts w Recurrent / Progressive Cerebral Anaplastic GliomasObjectives: To determine maximum tolerated dose of CPT-11 when administered following Temodar plus O6-benzylguanine To characterize any toxicity associated w combo of CPT-11 +…NCT00612638·Durham, North Carolina

TerminatedDietary, Herbal and Alternative Medicine in Glioblastoma MultiformeRATIONALE: Giving the herb Boswellia serrata after surgery and radiation therapy may slow the growth of any remaining tumor cells.NCT00243022·Cleveland, Ohio

RecruitingMagnetic Resonance Imaging for Improving Knowledge of Brain Tumor Biology in Patients With Resectable GlioblastomaThis clinical trial uses a type of imaging scan called magnetic resonance imaging (MRI) to study brain tumor biology in patients with glioblastoma that can be removed by surgery…NCT06090903·Los Angeles, California

WithdrawnMultimodality MRI and Liquid Biopsy in GBMPatients with a new diagnosis of high-grade glioma based on MRI, who are considered surgical candidates determined by neurosurgeons or patients with recurrent glioblastoma with…NCT04776980·Philadelphia, Pennsylvania

Active not recruitingA Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated GlioblastomaThe goal of this Phase 3 clinical trial is to compare the efficacy of niraparib versus temozolomide (TMZ) in adult participants with newly-diagnosed, MGMT unmethylated…NCT06388733·Birmingham, Alabama and 94 others

TerminatedTesting the Ability of AMG 232 (KRT 232) to Get Into the Tumor in Patients With Brain CancerThis phase I trial studies the side effects and best dose of navtemadlin in treating patients with glioblastoma (brain cancer) that is newly diagnosed or has come back (recurrent).NCT03107780·Birmingham, Alabama and 10 others

UnknownLonafarnib and Temozolomide in Treating Patients With Recurrent Primary Supratentorial GliomasRATIONALE: Lonafarnib may stop the growth of tumor cells by blocking the enzymes necessary for their growth.NCT00083096·Dijon and 2 others

RecruitingMultitracer [18F]Fluciclovine and 18F-FDG PET, and Advanced MRI for Metabolic Profiling of Glioblastoma* To perform metabolic phenotyping of treatment naïve and recurrent GBM by multitracer \[18F\]Fluciclovine and 18F-FDG PET.NCT06613841·Philadelphia, Pennsylvania and 1 other

CompletedA Phase I/II Study of the Photon Radiosurgery SystemThe standard treatment for children with brain tumors is surgical removal of the tumor followed by radiation to the brain and chemotherapy (medicines) given to shrink any…NCT00179907·Chicago, Illinois

RecruitingPersonalized Targeted Glioblastoma Therapies by ex Vivo Drug ScreeningPatient derived cell line (PDC) -based drug screening will be applied to formulate a personalized treatment approach.NCT06512311·Vienna, State of Vienna

CompletedRadiation Therapy Plus Chemotherapy in Treating Patients With Supratentorial Glioblastoma MultiformeRATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Chemotherapy uses different ways to stop tumor cells from dividing so they stop growing or die.NCT00002545·Birmingham, Alabama and 259 others

CompletedSorafenib Tosylate and Temsirolimus in Treating Patients With Recurrent GlioblastomaThis phase I/II trial studies the side effects and best dose of temsirolimus when given together with sorafenib tosylate and to see how well they work in treating patients with…NCT00329719·Anchorage, Alaska and 189 others

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