Brain Cancer Clinical Trials in Pittsburgh

Showing 101-120 of 181 trials

Cytochrome C Oxidase Activity in Newly Diagnosed Glioblastoma Multiforme (GBM)

NCT02997423

This is a multi-institutional, consortium-based, non-interventional prospective blinded endpoints clinical study to determine whether high activity of Cytochrome C Oxidase (CcO) in tumor specimens from subjects with newly diagnosed primary GBM is associated with shortened OS (primary outcome) and PFS (secondary outcome) times.

Glioblastoma

University of Iowa153 participantsStarted Nov 2016

Birmingham, Alabama, United States • Sacramento, California, United States • Miami, Florida, United States +16 more locations

COMPLETEDPhase 2< 1 mile

Bevacizumab With or Without Radiation Therapy in Treating Patients With Recurrent Glioblastoma

NCT01730950

This randomized phase II trial studies how well bevacizumab with or without radiation therapy works in treating patients with recurrent glioblastoma. Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry cancer-killing substances to them. Specialized radiation therapy that delivers a high dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue. It is not yet know whether bevacizumab is more effective with or without radiation therapy in treating patients with recurrent glioblastoma

Adult Giant Cell GlioblastomaAdult GlioblastomaAdult Gliosarcoma+1 more

Radiation Therapy Oncology Group182 participantsStarted Dec 2012

Birmingham, Alabama, United States • Phoenix, Arizona, United States • Phoenix, Arizona, United States +28 more locations

Cytochrome C Oxidase Activity in Newly Diagnosed Glioblastoma Multiforme (GBM)

Bevacizumab With or Without Radiation Therapy in Treating Patients With Recurrent Glioblastoma

Brain Cancer Trials in Other Cities

Temozolomide and Radiation Therapy With or Without Cediranib Maleate in Treating Patients With Newly Diagnosed Glioblastoma

Vorinostat and Radiation Therapy Followed by Maintenance Therapy With Vorinostat in Treating Younger Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma

Donepezil in Treating Patients Who Have Undergone Radiation Therapy for Brain Tumors

Safety and Efficacy Study of Lucanthone When Used in Combination With Temozolomide(TMZ) and Radiation to Treat Glioblastoma Multiforme(GBM)

Ipilimumab and/or Nivolumab in Combination With Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma or Gliosarcoma

Study of Tesevatinib Monotherapy in Patients With Recurrent Glioblastoma

Combination Adenovirus + Pembrolizumab to Trigger Immune Virus Effects

Rovalpituzumab Tesirine in Delta-Like Protein 3-Expressing Advanced Solid Tumors

Study of Marizomib With Temozolomide and Radiotherapy in Patients With Newly Diagnosed Brain Cancer

Phase 2 Study of Durvalumab (MEDI4736) in Patients With Glioblastoma

Evaluation of GLR2007 for Advanced Solid Tumors

Convection-Enhanced Delivery (CED) of MDNA55 in Adults With Recurrent or Progressive Glioblastoma

Dose Escalation Study to Determine the Safety of IFN-Beta Gene Transfer in the Treatment of Grade III & Grade IV Gliomas

Autologous Dendritic Cells Loaded With Autologous Tumor Associated Antigens for Treatment of Newly Diagnosed Glioblastoma

A Phase 1 Study Evaluating AMG 232 in Advanced Solid Tumors or Multiple Myeloma

Safety and Efficacy Study of Trans Sodium Crocetinate (TSC) in Newly Diagnosed Glioblastoma (GBM) Biopsy-Only Subjects

UNITE Study: Understanding New Interventions With GBM ThErapy

Gliogene: Brain Tumor Linkage Study

Other Conditions in Pittsburgh