Anxiety Clinical Trials

Showing 1861-1880 of 2,143 trials

Automatic Self Transcending Meditation (ASTM) in Patients With Dry Eye Disease

NCT03087006

Patients with dry eye disease (DED) will be randomized to Automatic Self Transcending Meditation (ASTM) plus Treatment as Usual (TAU) or TAU alone to assess changes in Health-related quality of life (HRQoL). HRQoL is a vital construct focusing on impact of health on quality of life. HRQoL data is used in economic evaluations, a component of health economics that compares the cost and consequences of alternative courses of action. This helps policy-makers make complex financial decisions. Along with HRQoL we will measure changes in extent of depression as well as anxiety. Previously published data lacks information of HRQoL in patients with DED. Through this study we shall attempt to correlate HRQoL in this population and assess if ASTM confers changes in HRQoL along with depressive and anxiety symptoms.

Eye DiseasesQuality of LifeDepression+1 more

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's256 participantsStarted Jul 2018

London, Ontario, Canada

COMPLETEDPhase 1

A First Time in Human Study of GSK586529 in Healthy Volunteers

NCT00703547

A single blind, randomized, placebo-controlled, crossover study in twenty four healthy male subjects. Subjects will be divided into two cohorts with alternate panel design. The study is investigating the safety, tolerability and pharmacokinetics of single oral escalating doses of GSK586529.

Depressive Disorder and Anxiety Disorders

GlaxoSmithKline21 participantsStarted Jan 2008

London, United Kingdom

Automatic Self Transcending Meditation (ASTM) in Patients With Dry Eye Disease

A First Time in Human Study of GSK586529 in Healthy Volunteers

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