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Browse 2,143 clinical trials for anxiety. Find studies that match your criteria and connect with research centers.
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NCT06523413
This randomized controlled trial aims to determine the effect of game activity and stress ball use on preoperative anxiety and vital signs in patients undergoing total knee arthroplasty. The primary purpose of the study is to evaluate the effect of these methods (game activity, stress ball use) on patients' anxiety and vital signs. The research involves three groups: one group will engage in a game activity, another group will use a stress ball, and the control group will receive no intervention. Patients over 18 years of age who pass the Mini-Cog test, demonstrate cognitive competence and meet other sampling criteria will be included in the study. Data will be collected using the State Anxiety Scale, a vital signs and pain level form, and a descriptive characteristics form.
NCT06736886
Breastfeeding is an important condition for the health of the mother and the baby, which is the most difficult for mothers after birth. Since it is an important practice for both the mother and the baby, the evaluation and reduction of the mother's stress factors can help the hospital to regulate the lighting of the breastfeeding room. In addition, setting the light color temperature to a more appropriate kelvin can make a positive contribution to the hospital in terms of costs. For this purpose, when researchers look at the literature, we have not come across a randomized controlled study examining the effect of the light color temperature applied during breastfeeding on the mother's stress, anxiety, peace and breastfeeding motivation. Researchers' purpose is to determine the effect of the light color temperature applied during breastfeeding on the mother's stress, anxiety, peace and breastfeeding motivation.
NCT06065735
The primary purpose of the study is to evaluate the potential effect of paroxetine on QTc interval following escalating doses in healthy participants. Participants with no history of cardiac abnormalities or mood disorders will be enrolled. During the study, participants will take paroxetine at three incremental dose levels. Participants will attend the clinic at screening, baseline, at the end of each dose level administration week, and a final study exit visit. While on treatment outside of clinic visits, participants will be followed-up via video-call. A concentration-QTc analysis will assess any potential correlation between paroxetine plasma concentration and QTc prolongation. In addition, the occurrence of any side-effects will be compared between on and off treatment.