Participants must meet the criteria for one of the following study groups:
Group A: Healthy participants without psoriasis (PsO) but at increased risk for PsO based on family history and/or smoking-related criteria as defined in the study protocol.
Group B: Participants with mild to moderate PsO (PASI ≤20) without psoriatic arthritis (PsA).
Group C: Participants with severe PsO (PASI \>20) without PsA.
Group D: Participants with mild to moderate PsA (DAPSA ≤28).
Group E: Participants with severe PsA (DAPSA \>28).
Group F: Healthy participants without PsO, PsA, or predefined risk for PsO.
Ability to understand the study information and provide written informed consent.
You may not be if
Pregnancy or breastfeeding.
Age below 18 years or above 65 years.
Strongly pigmented skin that may substantially attenuate the RSOM or MSOT signal.
Documented or suspected photosensitivity, light intolerance, contact dermatitis, or particularly sensitive skin.
Open or infected wounds at the measurement sites.
Presence of a cardiac pacemaker, insulin pump, or other implanted electronic device.
Regular or chronic use of immunomodulatory medications, including glucocorticoids, that may substantially affect inflammation or mast-cell activity, according to the criteria defined in the study protocol.
Refusal to participate or inability to provide informed consent.
