Juvenile systemic lupus erythematosus is a chronic multisystem autoimmune disease. Gastrointestinal involvement may be under-recognized and can be subclinical.
This observational study will measure fecal calprotectin and perform intestinal ultrasound in children with JSLE and age- and sex-matched healthy controls to assess subclinical gastrointestinal involvement.
Age
1–18
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
Children less than 18 years of age
Diagnosis of juvenile systemic lupus erythematosus according to SLICC criteria
Disease duration of at least 3 months
Age- and sex-matched healthy controls
Written informed consent from parents or legal guardians
You may not be if
\- Established diagnosis of inflammatory bowel disease or other primary gastrointestinal disorder
