Staatssekretariat für Bildung Forschung und Innovation SBFI
Horizon 2020 - European Commission
Age
18–80
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Aged ≥ 18 years and ≤ 80 years
Diagnosed with RA according to the EULAR 2010 criteria
Affection of at least one hand joint in the past (synovitis, tenderness, dactylitis, tenosynovitis)
Must provide and sign the study's Informed Consent prior to any study-related procedures;
Able to understand and interact with the study team
Agree to comply in good faith with all conditions of the recordings, and to attend all required study procedures
You may not be if
Deformation of the hands or patients who have undergone joint arthrodesis or arthroplasty
Known microcrystal disease (e.g. gout, calcium pyrophosphate deposition) if hands are affected or pre-existing immune-mediated rheumatic diseases such as systemic lupus erythematosus or Sjögren's disease in the past 2 years
Lymphoedema in arms or hands following an axillary lymph node dissection
Immunosuppressive therapy for other autoimmune conditions \<2 years ago
Immunosuppressive therapy for other autoimmune conditions with B-cell depletion \<5 years ago
Haematological or oncological treatments involving induction and / or maintenance chemotherapy \<5 years
Aged \>80 years
Participation in another investigation with an investigational drug or another MD within the 30 days preceding the trial or currently participating or planning to participate in an interventional trial
Inability to provide written informed consent
Severe cognitive impairment, severe psychiatric conditions or other inability to follow the procedures of the study
No regular access (weekly) to a smartphone
Adults who lack capacity to consent, known pregnant and breastfeeding women
Subjects for whom routine examination of the musculoskeletal system is not possible, or whose hands cannot be imaged (e.g., bandages that cannot be removed for hand picture taking, or injuries affecting the PIP joints both persisting for \> 27 days)
Enrolment of the PI, his/her family members, employees and other dependent persons
Other severe acute or chronic medical or psychiatric condition, or laboratory abnormality that would impart, in the judgment of the investigator, excess risk associated with study, or which, in the judgment of the investigator, would make the patient inappropriate for entry into this study
