The University of Texas Health Science Center, Houston
Age
3–18
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
confirmed Group A streptococcal (GAS) pharyngitis, defined by a positive rapid antigen detection test
Receiving care at either the University of Texas Pediatrics General Clinic or the Memorial Hermann Emergency Department
Written informed consent obtained from a parent or legal guardian, with assent from the child when developmentally appropriate and required by institutional policy.
You may not be if
Known allergy or hypersensitivity to penicillin, amoxicillin, or other beta-lactam antibiotics
Severe or complicated illness requiring hospitalization at presentation.
History of acute rheumatic fever, post-streptococcal glomerulonephritis, or other conditions for which prolonged antibiotic therapy is specifically indicated.
Immunocompromised state, including but not limited to: Active malignancy receiving chemotherapy, Solid-organ or hematopoietic stem cell transplant, Chronic systemic immunosuppressive therapy
Antibiotic use with activity against Group A Streptococcus within the preceding 7 days.
Inability to take oral medications or anticipated inability to complete outpatient therapy.
Clareo Health | Short Versus Standard Amoxicillin for Pediatric Strep Throat