The General Hospital of the Eighth Division (The Third Affiliated Hospital of Shihezi University Medical College)
Age
18–any
Sex
ALL
Healthy volunteers
Accepted
You may be eligible if
Household-level criteria:
The household includes at least one adult aged 18 years or older with diagnosed hypertension.
The household includes at least one adult aged 18 years or older without hypertension at baseline.
Household members primarily share cooking and meals.
All adult household members intended to be included in study evaluations provide written informed consent.
Participant-level criteria:
Aged 18 years or older.
Long-term resident of the study area with no plan to move away during the following 12 months.
Consumes most meals at home.
Provides written informed consent.
You may not be if
Household-level criteria:
The household is currently using low-sodium salt or another potassium-containing salt substitute on a long-term basis.
Any household member who routinely shares meals has a contraindication to potassium-enriched salt or is at increased risk of hyperkalemia, including chronic kidney disease, estimated glomerular filtration rate (eGFR) \<60 mL/min/1.73 m², a history of dialysis, or a history of hyperkalemia.
Any household member who routinely shares meals is pregnant.
Any household member who routinely shares meals has hyperthyroidism.
Participant-level criteria:
Currently participating in another interventional study that may affect blood pressure, sodium or potassium intake, or study outcomes.
Serious cardiovascular or cerebrovascular disease, severe liver disease, malignant tumor, severe mental illness, cognitive impairment, or another condition considered unsuitable for study participation.
Unable to complete follow-up visits, standardized blood pressure measurements, or required data collection.
Any other condition that, in the investigator's judgment, makes the individual unsuitable for participation.
Clareo Health | Household Salt Substitution for Hypertension Prevention and Control: The HOME-Salt Trial
